Protein Alignment CG6126 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 144/538 - (26%)
• Similarity: 247/538 - (45%)
• Gaps: 54/538 - (10%)

  Fly     9 DLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSS--LSVTPWNSS 71
            :|:..:||||.:|.....|..:..:.:...|.:...|....:..|      |:|  |:|.|..|.
Human   135 NLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYC------NTSWILAVGPHLSK 193

  Fly    72 A--ILAAIPLKPNGELESCLMFDPSSP---------GTNTTINC-ERYVYDTTYYKTSRTIDWNF 124
            |  :...||..|||...:|.|:.| .|         |.|.|..| :.::|... .|.|...:::.
Human   194 AEQLNLTIPQAPNGSFLTCFMYLP-VPWNLDSIIQFGLNDTDTCQDGWIYPDA-KKRSLINEFDL 256

  Fly   125 VCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVA 189
            ||.........|.:||.|:..|::....:.||:||......|.|..:|.|.|.||:..:..::..
Human   257 VCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAFMNSFHLYLFF 321

  Fly   190 RYLLGIVGSAGAY-ICGFVLTME-LVGPTK--RTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQ 250
            |:  ||..|...| |....|..| |||..:  ..:.|..|   ||.|.:|:.|....:|..|.|.
Human   322 RF--GISQSVVGYAISSISLATEWLVGEHRAHAIILGHCF---FAVGAVLLTGIAYSLPHWQLLF 381

  Fly   251 VIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAA 315
            ::.|:....|:.:.|.|.||||||.|:|:..||..::.....:|...||.:....:|..:::.
Human   382 LVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVNKKTIPSNLLDELQLPRKKV-- 444

  Fly   316 EEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYI 380
               :.|.:.|..:...|...||.:...||..|..|:.|||...:|..:.:....:..::|.|:.:
Human   445 ---TRASVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARL 506

  Fly   381 TIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG----------------STTSTAVVMAGKLL 429
            ..:|:|.::||:...:..:|...:.|::..::.:|                .:.:..|:|..:..
Human   507 CCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFS 571

  Fly   430 IAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISG 494
            :|.:..|.:.|:|||.|||:|.:.:||.|: |.::||:..| |::......:|..|..|:|:::.
Human   572 LAATVTVFFLYTAELLPTVLRATGLGLVSL-ASVAGAILSL-TIISQTPSLLPIFLCCVLAIVAF 634

  Fly   495 FWVMFLPETMNQPMPESI 512
            .....||||.:||:.||:
Human   635 SLSSLLPETRDQPLSESL 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	141/528 (27%)
		MFS	130..501	CDD:119392	101/390 (26%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	141/528 (27%)
		MFS	270..641	CDD:119392	100/382 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020