DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and HXT9

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	564	Identity:	131/564 - (23%)
Similarity:	214/564 - (37%)	Gaps:	151/564 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 IEGVDNSS---LSVTPWNSSAILAAIPLK-PNGELESCLMFD-----------PSSPGTNTTINC 104
            :.||:|:|   ||.|..||:::..|..:| .:.:.::.|..|           |.|..|...|.|
Yeast     1 MSGVNNTSANDLSTTESNSNSVANAPSVKTEHNDSKNSLNLDATEPPIDLPQKPLSAYTTVAILC 65

  Fly   105 ER-------YVYDT-----------------------TYYKTSRTIDWNFVCDRRWMGAIVQTVF 139
            ..       :.:||                       |||           ..:..||.|| ::|
Yeast    66 LMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYY-----------LSKVRMGLIV-SIF 118

  Fly   140 MLGVFTGAVTLGGLADKVGRK----TVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAG 200
            .:|...|.:.|..:.|..||:    ||   :|::.:.|.:.:..|.:::.:.:.|.:.|: |..|
Yeast   119 NIGCAIGGIVLSKVGDIYGRRIGLITV---TAIYVVGILIQITSINKWYQYFIGRIISGL-GVGG 179

  Fly   201 AYICGFVLTMELVGPTKRTVCGITFQAVFAGGIML--VAGWGA--LIPDRQWLQVIYGL------ 255
            ..:...:|..|:.....|......:|.:...||.|  ...:|.  .....|| :|..||
Yeast   180 IAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQW-RVGLGLCFAWTT 243

  Fly   256 ---HGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEE 317
               .|.:|      :.||||:|...|:..||...::|..:::.....:..||...||..:.   |
Yeast   244 FMVSGMMF------VPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLAEYDTIKAGIEL---E 299

  Fly   318 K--SSAGLSDLFRTPNLRMKTLNVCLCWFA----------NSLVYYGLSLSAGKLYGNPYLILFI 370
            |  .:|..|:|..|   :.|.....|....          |...|||.::.......:.:....|
Yeast   300 KLAGNASWSELLST---KTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSII 361

  Fly   371 MGLVEFPSYITIVFVLDRLGRRSITSTLMLGGG---LCCI-------VAAYIAQGST----TSTA 421
            :|:|.|.|....|:.::|.|||    |.:|.|.   |||.       |.....|||:    ||..
Yeast   362 IGVVNFFSSFIAVYTIERFGRR----TCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQG 422

  Fly   422 VVMAGKLLIAGSFAVIYNYS-----------AELFPTVVRNSAMGLGSMCARLSGAL----TPLI 471
               ||..:|..:...|::::           :|.||..|::..|.:.:....:.|.|    ||.|
Yeast   423 ---AGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFI 484

  Fly   472 TLLDSFDPKIPAVLFGVVAL----ISGFWV-MFLPETMNQPMPE 510
            |...:|       .:|.|.|    .:.|:| .|:|||....:.|
Yeast   485 TGAINF-------YYGYVFLGCLVFAYFYVFFFVPETKGLTLEE 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	130/562 (23%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	104/433 (24%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	114/501 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000