DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and GIT1

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_010022.1	Gene:	GIT1 / 850462	SGDID:	S000000695	Length:	518	Species:	Saccharomyces cerevisiae

Alignment Length:	491	Identity:	95/491 - (19%)
Similarity:	172/491 - (35%)	Gaps:	155/491 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 VQTVFMLGVFTGAVTLGGLADKVGRKT-VFCWSALFQLIIGVGV------AFIPEYFSFM-VARY 191
            |....::|:..|...:|..||...||: :...:|:  |:||..:      ..:|..|..: |.|.
Yeast    89 VSNAALVGIIFGQFFMGIAADYYSRKSCILVATAI--LVIGSALCAASHGTTVPGMFWMLTVMRG 151

  Fly   192 LLGI-VG------------SAGAYIC---GFVLTM------ELVGPTKRTVCGITFQAVFAGGIM 234
            |:|| ||            ||..|..   |.:|.|      ...||....:..|.:: :.:|...
Yeast   152 LVGIGVGAEYPTSTLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATIIFLIVYK-ICSGTKH 215

  Fly   235 LVAGWGALIPDRQWLQVIYGLHGCLF-LGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGI 298
            |.|.|          :.::.: ||.: |..:::     ||      .....::..|| ||. ..|
Yeast   216 LEAIW----------RTVFAI-GCFWPLSVFYF-----RW------KTATTEVYEKG-RIK-RNI 256

  Fly   299 PVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGN 363
            |    |::               .|...::      :.|..|..||....|.:...:.:..:..:
Yeast   257 P----YFL---------------ALKFYWK------RLLGTCGTWFMYDFVTFPNGIFSSTIISS 296

  Fly   364 PY-------------LILFIMGLVEFP--SYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIA 413
            ..             |:|.::.::..|  :|::     ||:||:   .|||.|      .:.||.
Yeast   297 VIKDQNDLVKVAEWNLLLGVLAVLGVPIGAYLS-----DRIGRK---YTLMFG------FSGYII 347

  Fly   414 QGSTTSTAVVMAGKLLIAGSFAVIYNY----------------SAELFPTVVRNSAMGLGSMCAR 462
            .|.....|.....|  |...|.:.|.:                |:|...|.||....||.::..:
Yeast   348 FGLIIGCAYDQLKK--ITPLFIIFYAFMNMLGNAGPGDMLGVISSEASATAVRGVFYGLSAVTGK 410

  Fly   463 LSGALTPLITLLDSFDP----------KIPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGEN 517
            :..     :..::.|.|          .|.|.:.|::.:|..::  |:|.::...:.:...:..|
Yeast   411 IGS-----VVGVECFQPIRDNLGARWTFIIAAICGLIGIIITYF--FVPHSLESDLMKQDVEFHN 468

  Fly   518 FGKGDTWFSQCAGRKKRQNSVYPDDPEQMVPLKNIE 553
            :...:.|    .|:.....:    |.|.||....:|
Yeast   469 YLVSNGW----TGKMGFDET----DEESMVRTIEVE 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	87/446 (20%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	86/437 (20%)
GIT1	NP_010022.1	MFS_PhT	48..454	CDD:340922	87/439 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000