DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and OCT5

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_178059.1	Gene:	OCT5 / 844279	AraportID:	AT1G79410	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	125/535 - (23%)
Similarity:	220/535 - (41%)	Gaps:	73/535 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVDYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSV 65
            :..|.:||.   .|.:||..||||..|..|:.......:...|...|.|...|....:.|
plant    23 LTFDKILEK---SLSDFGFSQFLQIVLVGLALTFDSQQIFITVFTDAYPTWHCLDHTICN----- 79

  Fly    66 TPWNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYD-TTYYKTSRTI-DWNFVCDR 128
                                          |.|.......|..:| ...:|....| :::..|..
plant    80 ------------------------------PATTDICKIPRSAWDWDGGFKGKSVISEFDLECSS 114

  Fly   129 RWMGAIVQTVFMLGVFTGAVTLGGLAD-KVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYL 192
            .::.::..:.|.:|...|.|.|..:.| .:|||.:..:|:....:.|:.:......:.:...:::
plant   115 SFLRSLPSSTFYVGSIVGGVVLAMIPDGSLGRKQLLFFSSFAMSLTGISIFLSSNIWIYSFLKFV 179

  Fly   193 LGIVGS-AGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVIY--- 253
            :|...| .|.|  ..||..|.:....|....:....:|..|.|.::|...|:....| :|:|
plant   180 IGFARSQTGTY--ALVLISERISTKWRPRATMVPFTLFVLGFMSLSGIAYLVRHASW-KVLYLCT 241

  Fly   254 ----GLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEY---YVQKAKQ 311
                |:|. :|:  :::..||||||.::|:..||::::.   ||:    |.::.|   ...:.:.
plant   242 SIPAGIHS-IFI--YFFALESPRWLHLEGKNKEAIEVLK---RIS----PANRGYLESVSSRLRP 296

  Fly   312 QAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEF 376
            :...|:.||..:.|||.......:...|.:..|...:.|||:.|:...:..|.|:...:..:||.
plant   297 KETLEQTSSYSIKDLFIIKWAFRRVTLVMIIMFGLGMSYYGVPLAVRDIKVNIYMSEALNAMVEL 361

  Fly   377 PSYITIVFVLDRLGRR-SITSTLMLGGG---LCCIVAAYIAQGSTTSTAVVMAGKLLIAG-SFAV 436
            |:::....:|::..|| |:....::||.   ||.:::.|   |.|.....:..|....|. .|.:
plant   362 PTFVVTPILLEQFSRRSSVLVNCLIGGASGVLCFVMSLY---GRTKIAFALELGSFFCARIGFNL 423

  Fly   437 IYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLP 501
            :..|..|||||.|||||..:......:.||..|||..|....|.:...:||......|.:.:.||
plant   424 MAIYLVELFPTCVRNSATMMLRQALVVGGACCPLIASLGRNVPSLSFAVFGFAMSGLGLFALLLP 488

  Fly   502 ETMNQPMPESIEDGE 516
            ||....:.:::|:.|
plant   489 ETKGLSLCDTMEEQE 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	119/513 (23%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	95/387 (25%)
OCT5	NP_178059.1	MFS_OCT_plant	83..488	CDD:340936	100/420 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020