DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and OCT1

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_565059.2	Gene:	OCT1 / 843656	AraportID:	AT1G73220	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	139/551 - (25%)
Similarity:	231/551 - (41%)	Gaps:	94/551 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVDYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHML-----SLVTV--AAVPEHR-----C 53
            :.||.|:|..:|.||          |.|:|..|...:..:     :|:::  .|.|..|     .
plant    43 LTVDEVIEQHIGALG----------FAQILHALLVSIAWIFDAQTTLISIFSDAQPAARLLATGA 97

  Fly    54 FIEGVDNSSLSVTPWNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSR 118
            .:||.....|:...|                       :...|.::|.::
plant    98 IVEGASLCGLASGEW-----------------------EWIGPKSDTVVS--------------- 124

  Fly   119 TIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADK-VGRKTVFCWSALFQLIIGVGVAFIPE 182
              :||.:|..:::.|:..|:|.:|...|:...|.|||. .|||.....|.:...:....::|.|.
plant   125 --EWNLICQHKFLVAVPSTLFFIGSLFGSGVYGYLADSWFGRKKTLLLSCVLTFVTAFAISFSPN 187

  Fly   183 YFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQ 247
            .:.:...|:..|...| |...|..||..|:||...|...|......|..|.:.:. ..|.:..:.
plant   188 VWVYAFLRFANGFFRS-GIGSCCIVLATEIVGKKWRGQVGQYGFFFFTLGFLSLP-LMAYLERKS 250

  Fly   248 WLQVIYGLHGCLFLGHWWWL----DESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYY--V 306
            | :.:|.:...|.||:...|    .||||||.::||..||:.::.|..|:||..:|.|....  :
plant   251 W-RNLYRIISFLPLGYAVCLLPFAYESPRWLLVKGRNKEAMVVLKKLARLNGKQLPADLSLVDPI 314

  Fly   307 QKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIM 371
            .:...|.::.||       .::|.....:.:.|.:..|.:..||||:.|:|..|..|.||.:.:.
plant   315 PERDDQTSSSEK-------FWKTKWAVKRIIMVMMAGFGSGFVYYGIQLNAENLNFNLYLTVAVN 372

  Fly   372 GLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAY---------IAQGSTTSTAVVMAGK 427
            .|:|||:.....|:|..:.||.:.|......|..|::.|.         |:.......||...|.
plant   373 ALMEFPAVFIGSFLLGVMNRRPLFSNSSYLAGFACLLCAVLSIHRVIRAISVAKWLQLAVEAVGF 437

  Fly   428 LLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALI 492
            :..:.::.|:|.|..|||||.|||:|:.|......|..:..||:..|......:..::|||.:::
plant   438 MASSTAYDVLYVYCVELFPTNVRNTAVSLLRQAFMLGASAAPLLVALGRESAMMSFIVFGVASVL 502

  Fly   493 SGFWVMFLPETMNQPMPESI------EDGEN 517
            ||...::|.||.|.|:.|::      |:.||
plant   503 SGIVSLWLRETRNAPLYETLAQQGKAEEIEN 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	129/522 (25%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	106/386 (27%)
OCT1	NP_565059.2	MFS_OCT_plant	102..511	CDD:340936	113/458 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm8406
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.150