DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and slc22a15.2

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001039179.1	Gene:	slc22a15.2 / 734018	XenbaseID:	XB-GENE-5824718	Length:	487	Species:	Xenopus tropicalis

Alignment Length:	514	Identity:	159/514 - (30%)
Similarity:	257/514 - (50%)	Gaps:	54/514 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LEDLMGKLGEFGKYQ-FLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNS 70
            |::....:||||..| .|..||.:|....|...|| :|.|.||||:.     :||..:|.:....
Frog     3 LDEAFLYIGEFGCCQKRLTAFLTLLQVYVACQSML-IVLVGAVPEYL-----IDNEDISASKEEY 61

  Fly    71 SAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIV 135
            :                                  ::::||..: ||...:|:.:.:..:...:.
Frog    62 T----------------------------------KHLHDTNNF-TSIVSEWHLIKNEAYKVNLA 91

  Fly   136 QTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAG 200
            .::|..|:..|.:..|.|:||:||:.|:.....|.:..|...|..|.|..|.|:|:.:||: :.|
Frog    92 SSLFFAGLLIGNILFGPLSDKLGRRPVYLSGLFFDITFGYCTALAPSYEVFAVSRFFVGIM-NGG 155

  Fly   201 AYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWW 265
            ..:..||||.|.||.:...:.|.....:||.||...|..|..|.:.:.|..:....|..|....:
Frog   156 MALVSFVLTQEYVGKSYWALTGSLTNLIFAVGIAFYALLGFYIRNWRTLAFVANSPGIFFFLLSF 220

  Fly   266 WLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTP 330
            .|.||||||:..|...|| :.|.:.:.: |:|:    |..|.|.|.......||:..:.||.:..
Frog   221 LLPESPRWLYSHGYTTEA-EGVLQSMAV-GNGV----ERPVVKLKSCPGTSSKSAHSVFDLVKYG 279

  Fly   331 NLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDR--LGRRS 393
            .||.:|:.:...|:..|||||||:|:||:|.||.||.:.:.||||.|::...::.:::  .|||.
Frog   280 VLRWRTILLMYIWYVCSLVYYGLTLNAGELKGNLYLNVALYGLVEVPAFPLCLYFIEKSWSGRRK 344

  Fly   394 ITSTLMLGGGLCCIVAAYIAQGS---TTSTAVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMG 455
            .|:..:...|..||...::.:.:   ...|.:.:.|||.::.:|.|:|.|::||:||||||:.:|
Frog   345 ATAGFLGFAGFACIFTIFLPETNGDLLNPTVLALFGKLSVSAAFNVVYIYTSELYPTVVRNAGLG 409

  Fly   456 LGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQPMPESIED 514
            :.:|..|..|.|:|.|..:.|.:|.:|.|.||:..:.:|...:.||||.|:|:.|||||
Frog   410 VCAMACRFGGILSPFIPTMKSLNPSMPFVAFGISGISAGILSLLLPETRNKPIAESIED 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	153/500 (31%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	121/375 (32%)
slc22a15.2	NP_001039179.1	MFS	48..455	CDD:391944	129/453 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930