DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and LOC685081

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_008764922.2	Gene:	LOC685081 / 685081	RGDID:	1583222	Length:	621	Species:	Rattus norvegicus

Alignment Length:	530	Identity:	170/530 - (32%)
Similarity:	265/530 - (50%)	Gaps:	38/530 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSAIL 74
            :|.::|:||.:|.....|..:....:...:.|.|.:.....|.|.:..|.|.:.:::.....|:
  Rat     7 VMAEVGDFGPFQVRVTILMGIPNFLSAFFVFSQVFMVLDEAHHCSVSWVKNHTFNLSAAEQLAV- 70

  Fly    75 AAIPLKPNGELESCLMFDPS----------SPGTNTTINCERYVYDTTY-YKTSR----TIDWNF 124
             :||....|..||||||.|.          |...|.|..|     |:.: |..:|    ..:::.
  Rat    71 -SIPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQAC-----DSGWDYPENRPPSLKNEFDL 129

  Fly   125 VCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVA 189
            ||:|..:....|:|||.|:..||:..|.:.|.:||:.......|...|.||..||:|.:..:||.
  Rat   130 VCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATAFVPSFELYMVL 194

  Fly   190 RYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAG--WGALIPDRQW--LQ 250
            .: ...:..||..:...:|..|.|||:.||...:..|:.||.|:|.:||  :|.    |.|  ||
  Rat   195 CF-FSAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNFALGLMALAGLAYGV----RNWRLLQ 254

  Fly   251 VIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAA 315
            :|......|.:.::|.|.||||||..|||..||..:|.|...:||.  |:..|...|...::..
  Rat   255 IIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGR--PLASELLNQLVPEKTG- 316

  Fly   316 EEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYI 380
               .|....||||.|.||..||.:...||.:||:||||....|....:.||...|.|:||.|:.:
  Rat   317 ---PSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEVPARL 378

  Fly   381 TIVFVLDRLGRR-SITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAGSFAVIYNYSAEL 444
            :.:.::::|||: |...||.|.|.:|.|:........|.:||:.:.||...:.:|.:.|.|:|||
  Rat   379 SSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSAAFTISYVYTAEL 443

  Fly   445 FPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQPMP 509
            .||::|.:.|||.|:.:|:.|.:|||:.||:.:...||.::||.:.:.:|.....||||..|.:.
  Rat   444 LPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETRGQTLK 508

  Fly   510 ESIEDGENFG 519
            ::::|.|..|
  Rat   509 DTLQDLEQGG 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	166/514 (32%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	129/375 (34%)
LOC685081	XP_008764922.2	2A0119	12..510	CDD:273328	166/515 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H80367
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.030