Protein Alignment CG6126 and Slc22a4

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 569
• Identity: 164/569 - (28%)
• Similarity: 271/569 - (47%)
• Gaps: 83/569 - (14%)

  Fly     4 DYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPW 68
            ||  ::::..||::|.:|.|.|||...|.:..|.:.:|:|.:|..|||||.:....|.|   :.|
  Rat     3 DY--DEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLS---SAW 62

  Fly    69 NSSAI------------------------LAAIPLKP-------NGELESCLMFDPSSPGTNTTI 102
            .:.:|                        .:|:.|:|       ..|.||||
  Rat    63 RNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQESCL------------- 114

  Fly   103 NCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSA 167
              :.:.|....:.::...:||.||:..|...:..::|.:||..|:...|.|:|:.|||.|
  Rat   115 --DGWEYSKDVFLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKV----- 172

  Fly   168 LF-QLIIGVGVAFIPEYFS-----FMVARYLLGIVGSAGAYICGFVLTMELVGPTKRT------V 220
            || .:.:..|.:|: :.||     |.|...::| :|....|:..|:|..|::..:.|.      |
  Rat   173 LFATMAVQTGFSFV-QIFSTNWEMFTVLFAIVG-MGQISNYVVAFILGTEILSKSVRILFSTLGV 235

  Fly   221 CGITFQAVFAGGIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVD 285
            |  ||   ||.|.|::..:...|.|.:.|.:...|.|...:..||::.||||||..|.|..||..
  Rat   236 C--TF---FAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQ 295

  Fly   286 IVAKGLRINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVY 350
            |:.|..::||...|.  ..:.....|:..:.::....:.|||:|.|:...|:...:.|...|:.|
  Rat   296 IIQKAAKMNGIMAPA--VIFDPLELQELNSLKQQKVFILDLFKTRNIATITVMSVMLWMLTSVGY 358

  Fly   351 YGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRR-SITSTLMLGGGLCCIVAAYIAQ 414
            :.|||:...|:|:.||..|:.||:|.|:|.|...:|..|.|| .|...|..|||:..:|......
  Rat   359 FALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPED 423

  Fly   415 GSTTSTAVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDP 479
            .:..|..:||.||..:..:|:::|.::|||:||:|||.|:|:.||.:|:...:.|....|.:::.
  Rat   424 YNFVSIGLVMLGKFGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNR 488

  Fly   480 KIPAVLFGVVALISGFWVMFLPETMNQPMPESIED-----GENFGKGDT 523
            .:|.:|.|.:.::.|...:|.||:....:||::|.     |...||..|
  Rat   489 LLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKST 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	154/538 (29%)
		MFS	130..501	CDD:119392	118/383 (31%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	154/538 (29%)
		MFS	123..510	CDD:119392	122/400 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm12322
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020