DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and LOC566640

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_009291426.1	Gene:	LOC566640 / 566640	-ID:	-	Length:	511	Species:	Danio rerio

Alignment Length:	553	Identity:	141/553 - (25%)
Similarity:	241/553 - (43%)	Gaps:	87/553 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSAILAAIPLKPNGELESCLMF--- 91
            |:| |..:|:.:::|:...  ...|...||..:|.:||  .|..:|...|  |..::|.:..
Zfish    11 LAG-TLQIHVFAILTLPIF--FTAFTFFVDVFTLHITP--CSVDIATKTL--NRSVDSNVSIFAS 68

  Fly    92 ------DPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTL 150
                  ||:|  :.|.:....:.:.                         |..:|.|:..|::..
Zfish    69 WTDNHSDPTS--SQTCLKANHFAHG-------------------------QATYMTGLLIGSLIG 106

  Fly   151 GGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGP 215
            |.|:||.|:|.:.........:..|.|||:|....::.||.:.| |.....:||.:.|.:|...|
Zfish   107 GALSDKYGKKILLICCTAIHAVATVIVAFLPYVPVYLTARAISG-VSCCAIHICTYSLGVEWSLP 170

  Fly   216 TKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQ--VIYGLHGCLFLGHWWWLDESPRWLWMQG 278
            ..|......|..:|:.|:|.:|....|  ...|:|  :..|:...|||..:::|.||||||.:..
Zfish   171 KYRIWPPTLFSFIFSLGMMGLAAVAFL--SSTWIQFHLALGIPQILFLPLYFFLPESPRWLLLNK 233

  Fly   279 RAAEAVDIVAKGLRINGSGIPVDKEYY------VQKAKQQAAAEEKSSAGLSDL--FRTPNLRMK 335
            |        .|.|....:....||.|.      |....|::.:|:.|:...|:.  |.:|.:.::
Zfish   234 R--------MKTLESYQNRSSKDKRYLDLLLHSVDNEAQKSLSEKSSTETRSNFTNFTSPIILLR 290

  Fly   336 TLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLML 400
            ...:....||::|.|||:..|.|....|.||..|..||.|.|| :.:.|:|.|.|||..|...:.
Zfish   291 LFIMSYIGFASALTYYGICFSIGSFGVNIYLAQFFSGLSEAPS-LLLPFLLKRWGRRPFTMGSLF 354

  Fly   401 GGGLCCIVAAYIAQGSTTSTAVV---MAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCAR 462
            ..|:.|:::..:::.......|:   :.|||.:..::.|...|..||||||:|...:|:.|:|.|
Zfish   355 LSGISCMLSLLVSKFCNMPALVMTLALMGKLCMQSTYCVSTLYGIELFPTVIRQKCVGVVSLCYR 419

  Fly   463 LSGALTPLITLLDSFDPK----IPAVL-FGVVALISGFWVMFLPETMNQPMPESIEDGENFGKGD 522
            ::..:..:::      |:    :||:: :....:|.....:.||||...|:|:::.:.|.  :..
Zfish   420 VACIINAVMS------PEGGIPLPAMISYSGGPIIGAALCLLLPETSGIPLPDTVHECEK--QPR 476

  Fly   523 TWFSQCA------GRKKRQNSVYPDDPEQMVPL 549
            ...|.||      .||..||:......|:..||
Zfish   477 LKLSCCACGSIKPTRKSTQNTEATFIKEECSPL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	129/506 (25%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	104/388 (27%)
LOC566640	XP_009291426.1	MFS	93..455	CDD:119392	103/379 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010