DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and oatx

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	562	Identity:	181/562 - (32%)
Similarity:	286/562 - (50%)	Gaps:	66/562 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLMGKLGEFGKYQFLQFFLQVLSG-LTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            ||:.::|.||::|.:...|..:.| |.|..::|:..| |.||||.|.|..|      .|..|.|.
Zfish     5 DLLDEVGGFGRFQMIHVTLLSIPGLLMASQNLLNNFT-AGVPEHHCRIPNV------TTAMNDST 62

  Fly    73 ---ILAAIPLKPNGELESC---------LMFDPSSPGTNTTINCE----RYVYDTTYYKTSRTID 121
               :.|.|||..:..|..|         |:.|..|.|..|.:..|    .:.||.:.:.:|...:
Zfish    63 TTLLRAFIPLDSSLTLSKCSRYKDTQWHLITDKLSHGNATELQTEGCADGWTYDKSEFISSIVSE 127

  Fly   122 WNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQL-IIGVGVAFIPEYFS 185
            |:.||..|.:..:.||::|.||.|||:..|||:|:.|||.:..|| .||| ::|...|..|.|..
Zfish   128 WDLVCTLRPLKQMSQTIYMGGVLTGAIIFGGLSDRFGRKALLIWS-YFQLALLGSFTALAPSYVV 191

  Fly   186 FMVARYLLGIVGSAGAYICGFVLTMELVGPTK-RTVCGITFQAVFAGGIMLVAGWGALIPDRQWL 249
            :.:.|:|.| :..:|..:....|.:|.: ||| ||:.|......|..|.|::||....:.|.:.:
Zfish   192 YCIFRFLTG-MSVSGVILNAVSLKVEWI-PTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDWRKI 254

  Fly   250 QVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDK------EYYVQK 308
            |:...|...:|..:.||..||.|||.:.||:.||:.::.:..:|||.....:|      |.::||
Zfish   255 QMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKPEMTEKITLEELESHMQK 319

  Fly   309 AKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGL 373
            ..|.:    ||...:.||.|||.:|..::.:.:.||:.|..||||::...|...|.||:..|.|.
Zfish   320 EVQSS----KSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLMQVIFGA 380

  Fly   374 VEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGS--------TTSTAVVMAGKLLI 430
            |:||:.:..:.:|..||||       |..|.|.:|:|.|...:        .|.||:.:.||...
Zfish   381 VDFPAKLVALLMLSFLGRR-------LTQGACLLVSASIIFANIFVPEDMQVTRTALAVLGKGFT 438

  Fly   431 AGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGF 495
            :.||..:|.::.||:|||:|.:.||..|..:|:.....|.:.:||...|.:|::::|..|:|:|.
Zfish   439 SASFTCVYLFTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIVYGGSAVIAGL 503

  Fly   496 WVMFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNS 537
            ....||||:|.|:|::|:|.|     :.|       :|:.|:
Zfish   504 IAFLLPETLNIPLPDTIDDVE-----EKW-------EKKNNT 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	172/527 (33%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	126/386 (33%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.060