Protein Alignment CG6126 and SLC22A15

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 172/590 - (29%)
• Similarity: 269/590 - (45%)
• Gaps: 95/590 - (16%)

  Fly     7 LEDLMGKLGEFGKYQ-FLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNS 70
            :|:....:||.|.|| :|.|.|.||..|......:.:..|.|.|.:.               |:.
Human     3 VEEAFQAVGEMGIYQMYLCFLLAVLLQLYVATEAILIALVGATPSYH---------------WDL 52

  Fly    71 SAILAAIPLKPNGELESCLMFDPSSPGTN-------TTIN---CERYVYDTTYYKTSRTIDWNFV 125
            :.:|   |.:.:|.         .|.|.:       .|.|   ..::|:.::.: ||...:|..:
Human    53 AELL---PNQSHGN---------QSAGEDQAFGDWLLTANGSEIHKHVHFSSSF-TSIASEWFLI 104

  Fly   126 CDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVAR 190
            .:|.:..:...:.|..|||.|.::.|.|:|:.|||.|:.......::..:...|.|.|..|.|.|
Human   105 ANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTR 169

  Fly   191 YLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQW--LQVIY 253
            :|:|:: :.|..:..|||..|.||.....:.|......||.||...|..|..|  |.|  |.::.
Human   170 FLVGMM-NGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFI--RSWRTLAILV 231

  Fly   254 GLHGCLFLGHWWWLDESPRWLWMQGR---AAEAVDIVAKGLRINGSGIPVDKEYYVQKAK----- 310
            .|.|.:......::.||||||:.|||   |.||:.::||..|               |.|
Human   232 NLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNR---------------KLKCTFSL 281

  Fly   311 -QQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLV 374
             ..|....:.:....||||...|...||.:...||..|||||||:||||.|.|:.|..|.:.||:
Human   282 THPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLI 346

  Fly   375 EFPSYITIVFVLDR--LGRRSITSTLMLGGGLCCIVAAYIAQGSTTST-AVV------MAGKLLI 430
            |.|||...::::::  .||:...|..:..|||.|::..::.:...|.. |||      :.|||.|
Human   347 EIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTI 411

  Fly   431 AGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGF 495
            :.:|.::|.|::||:|||:||..:|..||.:|:.|.:.|.|..|......:|.::||...|.||.
Human   412 SAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGL 476

  Fly   496 WVMFLPETMNQPMPESIEDGENFG---KGDTWFS-------QCAGRK-------KRQNSVYPDDP 543
            ..:.||||:|.|:.|:..|.:.:.   .|:...|       ||..::       :.:...|..|.
Human   477 LSLLLPETLNSPLLETFSDLQVYSYRRLGEEALSLQALDPQQCVDKESSLGSESEEEEEFYDADE 541

  Fly   544 E-QMV 547
            | ||:
Human   542 ETQMI 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	160/525 (30%)
		MFS	130..501	CDD:119392	127/390 (33%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	123/375 (33%)
		MFS_1	111..450	CDD:284993	118/356 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547		5/25 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930