DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and CG4459

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	572	Identity:	100/572 - (17%)
Similarity:	191/572 - (33%)	Gaps:	112/572 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVP-------------------EH--------- 51
            |.||::|.....|..|..:.:......::..|..|                   ||
  Fly    26 GSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVDRNHPLWQ 90

  Fly    52 ------RCFIEGVDNS-SLSVT---------PWNSSAILAAIPLKPNGELESCLMFDPSSPGTNT 100
                  |.|...|.|: |.|:.         .||:|                    ....||..:
  Fly    91 DARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNAS--------------------QSKEPGGQS 135

  Fly   101 TINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCW 165
            ::.||...:.|.|  .|....::.:|.||.:.|:.|:...||...|.:.......|:..:.:...
  Fly   136 SLPCEHVEHRTDY--KSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLL 198

  Fly   166 SALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICG-FVLTMELVGPTKRTVCGITFQAVF 229
            ..:.|:..|.....:..|...:..|.|..|. .|..|..| |:|.....|  |..:..:|...:|
  Fly   199 GMIGQIFCGNLTGLVDTYQLHIYFRCLTSIF-CALMYTSGQFILNDITSG--KARIIVVTLSELF 260

  Fly   230 -AGGIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWW--WLDESPRWLWMQGRAAEAVDIVAKGL 291
             :.|::|:........:  |..:...:...|.:..|.  |:.::||||....|...|:..:.:..
  Fly   261 WSMGLVLLPAISIYFDN--WSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESA 323

  Fly   292 RINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGL--- 353
            ..|...:|:..:..:.........:.|.......::.....|.:.:.:.|.| ..::|.|.:
  Fly   324 TYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIW-GGAMVLYNIILL 387

  Fly   354 ---SLSAGKLYGNPYLILF--IMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIA 413
               :|.|.:::.|...:.|  ::||     ::.:..:|...........||:..||...:...:.
  Fly   388 MIRNLGAQQVHVNTAAMGFAEMVGL-----FVGLYLILYTRRHWRWAGNLMIIAGLSTYLIWLLP 447

  Fly   414 QGSTTSTAV------VMAGKLLIAGSFAVIYNYSAELFP----TVVRNSAMGLGSMCARLSGALT 468
            :....|..|      .:..|:..:.|.||:...::|:..    .|:..|.:....:|.    ...
  Fly   448 ETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCL----LFC 508

  Fly   469 PLITLLDSFDPKIPAVLFGVVALISG---------FWVMFLPETMNQPMPES 511
            |.::.|......:|..:...:..|.|         :|....|:....|.|.:
  Fly   509 PFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNT 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	99/569 (17%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	68/401 (17%)
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	96/546 (18%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	67/390 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020