DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and CG17751

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	134/555 - (24%)
Similarity:	245/555 - (44%)	Gaps:	62/555 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSS 71
            |:.::.|.|.||.||.|...|...:.:.:.:|..|...::..|.|||      :......| ||:
  Fly     3 LQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRC------SRPEDYQP-NST 60

  Fly    72 AILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQ 136
            ::|:.          |.:.||.....|:.  :.||   ::.|...:..::|  |||..:..|:.|
  Fly    61 SLLSC----------SVMQFDKEFKCTSW--DFER---ESNYESITTELEW--VCDDAYKLAVGQ 108

  Fly   137 TVFMLGVFTGAVTLGGLADKVGRKTVFCWSAL-------FQLIIGVGVAFIPEYFSFMVARYLLG 194
            :.|.:|...|::..|.|||::||......|.|       |...:|    .:| :|||  .|::.|
  Fly   109 SFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVG----SLP-WFSF--TRFISG 166

  Fly   195 IVGSAGAYICGFVLTMELVGPTKRTV-CGITFQAVFAGGIML---VAGWGALIPDRQWLQVIYGL 255
            :.... .|:..::|..|.:.|..||. ..|.....:..|:|:   :|.|.....:..|...:..|
  Fly   167 LFMDT-QYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPAL 230

  Fly   256 HGCLFLGHWWWLDESPRWLWMQG---RAAEAVDIVAK--GLRINGSGIPVDKEYYVQKAKQQAAA 315
            ...||.   .:|.||..||..:|   :|.:::..|||  |.:::.|......::|.:|...   :
  Fly   231 GMLLFP---VFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNN---S 289

  Fly   316 EEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYI 380
            :.|||.....:.|||.||..|:.:.:.....::.:..||.:...:..:|:.:....|....|:.:
  Fly   290 QNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGL 354

  Fly   381 TIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAGSFAVIY------N 439
            ||:...:::||:.:....:..|.:......|:......|...|:.|.::..|.:..:.      .
  Fly   355 TIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQ 419

  Fly   440 YSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETM 504
            |:||:.||.|:...:....:........:..|..|.:|...:|:::...:.||.....:.||||:
  Fly   420 YAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETL 484

  Fly   505 NQPMPESIEDGENFGKGDTW-FSQCAGRK-KRQNS 537
            ::.:|:::|:||.|.||:.| |..|..|: |.|.|
  Fly   485 HKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKS 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	118/516 (23%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	86/392 (22%)
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	118/516 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	84/385 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	3	3.010