DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and Balat

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	594	Identity:	169/594 - (28%)
Similarity:	286/594 - (48%)	Gaps:	80/594 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVL--SGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNS 70
            ::::.::|.||.||.: ....||  :.|....|..|.:.:||.|:|.|.:..::       ||..
  Fly     4 DEVLREVGSFGLYQKV-IICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELE-------PWTQ 60

  Fly    71 SAIL----AAIPLKPNGELESCLMFDPS---------------------------SPGTNTTINC 104
            ..:.    .:||...||....|.|:..:                           .|.|...:.|
  Fly    61 DYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPC 125

  Fly   105 ER-YVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSAL 168
            :. :.||.:.|.::...:||.||||.::..:...||.:|...|....|.|.|..||:..|....|
  Fly   126 QHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLL 190

  Fly   169 FQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGI 233
            .::|.....||...|::::..|:::|:...| .....:||.:|||||.:|..|.|.....::.|:
  Fly   191 LEIIACAASAFAWNYYTWLGLRFVVGLTVPA-ILASPYVLAIELVGPERRVFCTIVSNIAYSLGL 254

  Fly   234 MLVAGWGALIPDRQWLQV-------IYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGL 291
            :::||...::  |.|.::       :..|..|.|:     |.||||||...|:...|:.|:....
  Fly   255 VVLAGVIYIV--RDWRELSLAVSMPLLMLFSCFFV-----LPESPRWLMAVGKTRRAIKILKVMA 312

  Fly   292 RINGSGIPVDKEYYVQKAKQQ----AAAEEKSSA----GLSDLFRTPNLRMKTLNVCLCWFANSL 348
            |:|  |:.|::: :|::.:::    .|||.|||.    |:.||||.||:|.|||.:.|.||||:.
  Fly   313 RVN--GVRVNRD-FVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTS 374

  Fly   349 VYYGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIA 413
            ||.|||..|..|.|:.....|:.|.||.|:|:.:...|...|||.|....||.||:.| ||.::.
  Fly   375 VYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVAC-VATFLY 438

  Fly   414 QGSTTSTAVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFD 478
            ...|  ..:...||:.|:.||.|:...::||:|||||...|...|:.:.:...:.|:|..:....
  Fly   439 PDIT--LLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQM 501

  Fly   479 PKIPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGE----NFGKGDTWFSQCAGRKKRQNSVY 539
            ..:|.::.|.:.::.||..:.||||.|:.:|:::|:||    :|     ....|...:::.|::.
  Fly   502 LVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSF-----LLCCCVESERKPNNIR 561

  Fly   540 PDDPEQMVP 548
            ....::::|
  Fly   562 ASPKKRILP 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	161/543 (30%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	121/385 (31%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	130/409 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	225	1.000	Domainoid score	I682
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm8406
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
	8	8.090