DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and CG3168

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	115/530 - (21%)
Similarity:	202/530 - (38%)	Gaps:	121/530 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 GELESCLMFDPSSPGTNTTINCERYV----YDTTYY---------KTSRTID---WNFV-----C 126
            |..:|..:.:|::|   ...|.||.:    |...:|         .||..:|   .:|:     |
  Fly   119 GRKKSVPLPEPTAP---IVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAEC 180

  Fly   127 D-------RRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYF 184
            |       :.|:.:|:    .:|:..||...|.:||..|||.|....:.......|..:|...|.
  Fly   181 DLDLNTETKGWLNSII----FIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYS 241

  Fly   185 SFMVARYLLG-IVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVF-AGGIMLVAGWGALIPDR- 246
            .||:.|:|.| .:|.:|..|..:....:   |..:....::|.|.| ..|.:.||....||..|
  Fly   242 FFMLFRFLNGAALGGSGPVIWSYFAEFQ---PKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRT 303

  Fly   247 -----------QW--LQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGI 298
                       .|  ..::..|...|.....::|.|||::|..:|:...|:.|. :|:.:..:..
  Fly   304 IGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIF-RGIFVTNTKR 367

  Fly   299 PVDKEYYVQKAKQQAAAEEKSS----------AGLSD----LFRTPNLRMKTLNVCLCWFANSLV 349
            ..| ||.|...:......|.:.          :|:.|    ||::|.||...:::.:. |...:.
  Fly   368 RPD-EYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITIN-FTFHIG 430

  Fly   350 YYGLSL-------------------SAGKLYGNPYLI-------------------LFIMGLVE- 375
            ||||.:                   |||......|::                   :|:..|:.
  Fly   431 YYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISL 495

  Fly   376 ---FPSYITIVFVLDRLGRR--SITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAGSFA 435
               .|:.:..:..:|.|||:  .|..|:..|   .|....|..:.|..:..|.......|:.:.|
  Fly   496 ASALPANLLAILGMDMLGRKFFLIAGTMTAG---ICSALMYFVRSSVQNLVVSAIFSGAISAANA 557

  Fly   436 VIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLI--TLLDSFDPKIPAVLFGVVALISGFWVM 498
            .:.....|:|||.:|.:.:.:..:.|||.|.:..::  .|||::.|. |..:...:.:..|...:
  Fly   558 ALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPS-PTFIVSGLLIGGGLMCL 621

  Fly   499 FLPETMNQPM 508
            .||.|..:.:
  Fly   622 LLPNTTRKEL 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	115/530 (22%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	97/446 (22%)
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	98/461 (21%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	103/482 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040