DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and Slc22a17

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_803156.2	Gene:	Slc22a17 / 305886	RGDID:	631405	Length:	520	Species:	Rattus norvegicus

Alignment Length:	494	Identity:	127/494 - (25%)
Similarity:	205/494 - (41%)	Gaps:	62/494 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NSSLSVTPWNSSAI-LAAIPLKPNGELESCLMFDPS-----SPGTNTTINC-ERYVYDTTYYKTS 117
            |:|....|.|||.: :|...|..:.........|||     .|..|   :| :.:.|:.....|:
  Rat    23 NASGWEQPPNSSGVSVAGAALAASAASRVVTSTDPSCSGFAPPDFN---HCLKDWDYNGLPVLTT 84

  Fly   118 RTI-DWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIP 181
            ..| .|:.|||..|...:.|.:|:||..:|.:.||..||:.||:.:...:.......|||.|...
  Rat    85 NAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149

  Fly   182 EYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDR 246
            .....|..|:|||.: .||..:..:::.:||..||:|....:..:.|..||..|..|...:..|.
  Rat   150 SSTGIMTLRFLLGFL-LAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDW 213

  Fly   247 QWLQVIYGLHGCLFLGHWW---WLDESPRWLWMQGRAAEA---VDIVAKGLRINGSGIPVDKEYY 305
            ::||.:......|||.:.|   :| ||.|||.::.:..||   :.|:|:..|.:|..:..:.:..
  Rat   214 RFLQRMITAPCILFLFYGWPGLFL-ESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEA 277

  Fly   306 VQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLV------------------YYG 352
            :|:.:........|:...:.|.   |.|....|:.:..|.|.:.                  :|.
  Rat   278 LQELENTCPLPTTSTFSFASLL---NYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYL 339

  Fly   353 LSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAA----YIA 413
            .||.|.   |...|....:|:           .:||.|||.|....|...|:..:|..    |:.
  Rat   340 CSLLAS---GTAALACVFLGV-----------TVDRFGRRGILLLSMTLTGIASLVLLGLWDYLN 390

  Fly   414 QGSTTSTAVVMAGKLLIAGSFAVIYN-YSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSF 477
            ..:.|:.:|:   .|..:.:.|::.. .:||:.||.||...:||......|.|...|...|....
  Rat   391 DAAITTFSVL---GLFSSQASAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSCPAQRLHMGH 452

  Fly   478 DPKIPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGE 516
            ...:..|:....||:....:|.||||..:.:||.:.|||
  Rat   453 GAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	122/486 (25%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	97/399 (24%)
Slc22a17	NP_803156.2	MFS	106..476	CDD:119392	95/391 (24%)
Slc22a17	NP_803156.2	2A0114	111..475	CDD:273326	92/385 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010