Protein Alignment CG6126 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 542
• Identity: 161/542 - (29%)
• Similarity: 269/542 - (49%)
• Gaps: 52/542 - (9%)

  Fly     7 LEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVT---PW 68
            |.|.:|.||.|..:|.:.....:|...|  .:||...: ||||.|||::..:|||:...:   ..
Mouse     6 LLDRVGGLGRFQLFQTVALVTPILWVTT--QNMLENFS-AAVPHHRCWVPLLDNSTSQASIPGDL 67

  Fly    69 NSSAILA-AIPLKPNGELESCLMF--------DPSSPGTN----TTINCE-RYVYDTTYYKTSRT 119
            ....:|| :||..|:.:...||.|        :.::..||    .|..|| .:|||.:.::::..
Mouse    68 GPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHSTFRSTIV 132

  Fly   120 IDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEY- 183
            ..|:.||:.:.:..:.|::|:.|:..||...|..:|:.||:.|..||.|...:.|...||:|.:
Mouse   133 TTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFP 197

  Fly   184 ----FSFMVARYLLGIVGSAGAYIC------GFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAG 238
                |.|::|..:.|::.:..:.:.      |..|.|.|      ...|.:|..|..|.:    .
Mouse   198 LYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTL------NALGFSFGQVLTGSV----A 252

  Fly   239 WGALIPDRQW--LQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRIN---GSGI 298
            :|.    |.|  ||:.......||..:.|||.||.|||...|:..:.:..:.:...:|   ..|.
Mouse   253 YGV----RSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEGD 313

  Fly   299 PVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGN 363
            .:..| .::.|.::..:.:|:.|.|..|..||.||.:|:...|||||....:|||:|....|..|
Mouse   314 TLTME-VLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALGSN 377

  Fly   364 PYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG-STTSTAVVMAGK 427
            .:|:..::|:|:||.....:.::.|||||....:.::..|||.:....:..| ....:|:.:.|.
Mouse   378 IFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGL 442

  Fly   428 LLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALI 492
            ..:.|:|..|..:|:||||||:|.:|:||..:.||....|.||:.||..:...:|.:::|||.::
Mouse   443 GCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVL 507

  Fly   493 SGFWVMFLPETMNQPMPESIED 514
            ||...:.||||.|.|:|::|:|
Mouse   508 SGLAALLLPETKNLPLPDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	154/528 (29%)
		MFS	130..501	CDD:119392	112/387 (29%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	157/532 (30%)
		MFS	147..516	CDD:119392	112/383 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060