DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and suex-2

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_501556.2	Gene:	suex-2 / 183742	WormBaseID:	WBGene00008271	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	509	Identity:	118/509 - (23%)
Similarity:	190/509 - (37%)	Gaps:	98/509 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 ELES-CLM-FDPSSPG---TNTTINCERYVYD-TTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLG 142
            :|:| ||| :|.::..   .|.|.|..:.:.| :..:..|...::...| ....|..:.|...:|
Worm    47 KLQSKCLMDYDHNAQNLCPVNMTENASKCIADHSRLFFRSAQFEYQQDC-TGLNGFSLSTATFIG 110

  Fly   143 VFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFV 207
            ...|.:.||.||||.||:|::..|.||.:...|..|.|...:||.:.|.|:|| ..:|....|:.
Worm   111 TLLGNIALGFLADKYGRRTIYLSSLLFGIPCVVLSAAITNIYSFYIFRILIGI-SVSGTLTVGWT 174

  Fly   208 LTMELVGPTKRTVCGITFQAVFAGGIMLVAGW--------GALIPDRQWLQVIY--GLHGCLFLG 262
            ...|::.|.:|.            .|:..:.|        |.....::|....|  ....||.|.
Worm   175 YATEMISPNRRL------------RILAFSNWPNARMIQVGLAYISQEWKTATYICAAVSCLSLP 227

  Fly   263 HWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLF 327
            ...:|.|||.||..:.:...| ....|.||..|.        :.........|..|.:.  :.:.
Worm   228 ILIYLPESPIWLDQKQKYKNA-SKARKRLRKIGK--------FYSNEHSTVVANRKFTP--TRIL 281

  Fly   328 RTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLV----EFPSYITIVFVLDR 388
            :.|.||.....:...:|...|..|...|:...:..|.||..|:.|||    :|...:|..: |..
Worm   282 KDPKLRNSFFMIIFMYFYVGLAVYITDLNGADMTKNLYLGQFLSGLVLSIAQFIIGMTEPY-LTG 345

  Fly   389 LGRRSITSTLMLGGGLC--CI--------------VAAYIAQGSTTSTAVVMAGKLLIAGSFAVI 437
            ||||.:.........||  ||              ::||....:|.|..:..|
Worm   346 LGRRVLFLIAQFIAMLCYICILICLYLNWKGSFLYLSAYTLAYATQSLCLEAA------------ 398

  Fly   438 YNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLD-SFDPKIPAVLFGVVALISGFWVMF-- 499
            |....||.||.||.:|....::|.::...|..|...|. :::|.:..:...:..:  |..::|
Worm   399 YLSLVELMPTDVRATAGSTANICMKIGTILATLTKPLKFAYEPSLFFINLSICTI--GMILVFFK 461

  Fly   500 LPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDD--PEQMVPLKN 551
            |.|:....|....:..:|..                 |.:.::  |.|.:.|||
Worm   462 LEESREADMKMIGQTNDNIA-----------------SAHNEEEMPNQTIQLKN 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	111/464 (24%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	96/403 (24%)
suex-2	NP_501556.2	MFS	108..460	CDD:391944	93/390 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910