DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and Y51A2D.18

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_507620.2	Gene:	Y51A2D.18 / 180202	WormBaseID:	WBGene00013083	Length:	550	Species:	Caenorhabditis elegans

Alignment Length:	569	Identity:	131/569 - (23%)
Similarity:	234/569 - (41%)	Gaps:	93/569 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KYQFLQFFLQVLSGL----TAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSAILAAIPL 79
            |.:||:...:.:.||    ..|.::| ||.:||              .|.:.|..||...
Worm    21 KLEFLEKEPEQVHGLDDYIQMGKYVL-LVCLAA--------------ELLILPQVSSMFY----- 65

  Fly    80 KPNGELESCLMFDPSSPGTNTTINCERYVYDT----------------------TYYKTSRTIDW 122
                     :|:..::|   ..|:|:..|:|:                      .|...|..:::
Worm    66 ---------MMYAGAAP---RVISCDNIVFDSLLEGKEICFELDKMGNCSHPEFQYQFRSINVEY 118

  Fly   123 NFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFM 187
            |:.|:...:.....:|.|.||.||::..|.::|..|||.....::|..||..:.|........|.
Worm   119 NYFCNTSKLVKNSISVQMFGVLTGSIVFGQISDSFGRKIGSQVASLGMLIGWLIVVQSRNLLHFT 183

  Fly   188 VARYLLGIVGSAGAYICGFVLTMELVGPTKRTV---CGITF---QAVFAGGIMLVAGWGALIPDR 246
            ::|.::|........|.. |..||.: |.|..:   ..||:   ..:::....|.:.|.:|
Worm   184 ISRTIVGFFTGGSISIIN-VFIMENI-PKKHRMWINMAITWSPNMPIYSYFAWLASDWKSL---- 242

  Fly   247 QWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEY----YVQ 307
            .::.....:.|.||.  .:::.||||||..:|:.:|||.::.:.|:.:.....:.:::    .::
Worm   243 AYINAFMCIPGILFF--QFFIHESPRWLVTRGKISEAVQVLQRQLKTSNQENLIHEDFEENLRME 305

  Fly   308 KAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMG 372
            .||.||....|:......||.||.|.:.|:.:...:.|.|::.||:..:..||.|:.|......|
Worm   306 YAKTQAQNTRKTKFSYYHLFVTPKLAITTIVLAYSYCATSIINYGVLFNMEKLSGSIYWNSVYTG 370

  Fly   373 LVEFPSYITIVFV---LDRLGRRSI-TSTL-MLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAG 432
            |:.:...::..:.   ...:||:.| ||.| ::...|..:|.:|....:.....|:....||.:.
Worm   371 LMRYACNLSFGYADLKFKSIGRKFIHTSGLVIIVLSLSLVVGSYALHLNHEMKDVIRISILLASS 435

  Fly   433 SFAVIY----NYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALIS 493
            ..:.||    ..|||||||.:|........:..|:...|:|.|..|..:...:|.....:.:||.
Worm   436 MTSQIYIADGIVSAELFPTPIRTIGYAFLQLWNRVGVVLSPFIFYLADYWLALPFCFMILFSLID 500

  Fly   494 GF-WVMFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPD 541
            .| :...||||..:.:.|.:.....:     ||.  ||:::......||
Worm   501 TFSFECLLPETKGRHLVEHMPPRHQW-----WFG--AGKEEIVEVEEPD 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	124/536 (23%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	95/390 (24%)
Y51A2D.18	NP_507620.2	2A0119	24..519	CDD:273328	123/534 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010