DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and Svop

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_599231.3	Gene:	Svop / 171442	RGDID:	620277	Length:	548	Species:	Rattus norvegicus

Alignment Length:	576	Identity:	132/576 - (22%)
Similarity:	219/576 - (38%)	Gaps:	146/576 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWN 69
            :::||.:..:| ||::|:.   |.||:||.                                 |.
  Rat    68 FMVEDAVEAIG-FGRFQWK---LSVLTGLA---------------------------------WM 95

  Fly    70 SSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAI 134
            :.|:          |:....:..|.       ::||                |..   ..|..|:
  Rat    96 ADAM----------EMMILSILAPQ-------LHCE----------------WRL---PSWQVAL 124

  Fly   135 VQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSA 199
            :.:|..:|:.:.:...|.::|:.||||....|..:.|..|:..||.|.|...:|.|.|:|.  ..
  Rat   125 LTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGF--GI 187

  Fly   200 GAYICGFVLTMELVGPTKRTVC----------GITFQAVFAGGIMLVAGWGALIPDRQWLQVIYG 254
            |.......|..|.:....|..|          |..|:.:.|..:|...||       :||.::..
  Rat   188 GGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPSLGW-------RWLLLLSA 245

  Fly   255 LHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEEKS 319
            ....:|....:||.||.|:..:.|...:|:..:.:....||:.:|:.|         ...:.::.
  Rat   246 APLLVFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGK---------LIISRQED 301

  Fly   320 SAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGL---------------------------SLSA 357
            ...:.||| ||:.|..||.:...||:|:..||||                           ||:.
  Rat   302 RGKMRDLF-TPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISSRKKAVEAKCSLAC 365

  Fly   358 GKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAV 422
            ..|....|:.|....|.|||..:..::|:|||||:...:...:...||.:: .:|..|....|.:
  Rat   366 EYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFVIFSLCSLL-LFICIGRNVLTLL 429

  Fly   423 VMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLG--SMCARLSGALTPLI--TLLDSFDPKIPA 483
            :...:..|:|.|...|.|:.|::||..|  |:|||  |..||:...:||.|  .:|:| ...:..
  Rat   430 LFIARAFISGGFQAAYVYTPEVYPTATR--ALGLGTCSGMARVGALITPFIAQVMLES-SVYLTL 491

  Fly   484 VLFGVVALISGFWVMFLP-ETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSV 538
            .::....|::.....||| ||..:.:.||        ....|..:..||......|
  Rat   492 AVYSGCCLLAALASCFLPIETKGRALQES--------SHREWGQEMVGRGTNSTGV 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	124/536 (23%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	104/411 (25%)
Svop	NP_599231.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	523..548		4/17 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910