Protein Alignment CG6126 and Slc22a27

DIOPT Version :10

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_017173565.1
• Gene: Slc22a27 / 171405
• MGIID: 3042283
• Length: 576
• Species: Mus musculus
• Alignment Length: 569
• Identity: 153/569 - (26%)
• Similarity: 258/569 - (45%)
• Gaps: 61/569 - (10%)

  Fly     8 EDLMGKLGEFGKYQFLQF-FLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSS 71
            ::|:.::|..|::|.||. ||.:|:.:.. .|:......||:|.|||::..:||.:.|.   |.|
Mouse    29 QELLNQVGSLGRFQILQIVFLLLLNAIVV-PHIAMENFTAAIPNHRCWVPILDNDTASD---NGS 89

  Fly    72 AILA-------AIPLKPNGELESCLMF---------------DPSSPGTNTTINCERYVYDTTYY 114
            .||:       :|||..|...|.|..|               :.|.|.|...:  :.:|||.:.:
Mouse    90 RILSQDDLLRISIPLDSNLRPEKCRRFAQPQWHLLHLNGTFSNVSEPDTEPCV--DGWVYDRSNF 152

  Fly   115 KTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAF 179
            .::...:|:.||:.:.:.::.:..||:|:|.|.:..|.|:|::|||.:...:.|...|....|||
Mouse   153 LSTIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRLGRKFILTCALLQFAITETCVAF 217

  Fly   180 IPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIP 244
            .|.:|.:...|:|.|: ......:...:|.:|...|...|:...........|.|:.||...|.
Mouse   218 APSFFIYCSLRFLAGL-SVEPILVNSHLLMLEWTSPKFLTMMAALLSCAPNIGYMISAGLAFLF- 280

  Fly   245 DRQW--LQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQ 307
             |.|  ||:...:....||....||.||.|||.:..:..:.:..:.|...:||.....|....:.
Mouse   281 -RIWHHLQLTMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGDLTMEIV 344

  Fly   308 KAKQQAAAE-EKSSAGLSDLFRTPNLRMKTLNVCLCWFAN---SLVYYGLSLSAGKLYGNPYLIL 368
            :...:|..| .|:...|.|||.|..||.:   :|:..|..   ::..:||::....|..|..|:.
Mouse   345 RTSMKAELEAAKTKPSLRDLFHTSILRKR---ICVLSFMRLFFTVSIFGLAVHLQHLSSNIILLQ 406

  Fly   369 FIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAGS 433
            |::..:.....:...|||:.:|||.....||...|:..::|.::.|...| ..::||  .|..|.
Mouse   407 FLISALAILVSVIGPFVLNHIGRRITYLVLMSLRGIFILIAVFVPQEMQT-LRIIMA--TLAEGI 468

  Fly   434 FAVIYNYSA----ELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISG 494
            .::....|.    ||.||.:|.:|:|:..........|:||..||.::...:|.:.:|..::.:.
Mouse   469 SSLCVGVSRLHTNELLPTTLRATAVGVIGFFGNSGSFLSPLFMLLATYYANMPWIFYGGFSIFNA 533

  Fly   495 FWVMFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDP 543
            |.|..||||.|||:|:|..|     .|:.|.....|:|        :||
Mouse   534 FTVFLLPETKNQPLPDSTHD-----VGNDWKESRKGKK--------EDP 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	143/527 (27%)
Slc22a27	XP_017173565.1	MFS_OAT	134..540	CDD:340932	107/416 (26%)