DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and Ust5r

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	574	Identity:	158/574 - (27%)
Similarity:	258/574 - (44%)	Gaps:	70/574 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            ::|:.::|..|::|.||.....|..::...|.......||:|.|||::..:||.::|.   |.|.
  Rat     4 QELLNQVGSLGRFQILQMAFVFLINVSVVPHSTIENFTAAIPSHRCWVPILDNVTVSD---NHSR 65

  Fly    73 IL-------AAIPLKPNGELESCLMF-----------DPSSPGTNT-TINC-ERYVYDTTYYKTS 117
            ||       .:|||..:..|:.|..|           |..|..|.. |..| :.:|||.:.:.::
  Rat    66 ILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSVTEADTEPCVDGWVYDRSNFHST 130

  Fly   118 RTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPE 182
            ...:|:.||:.:.:.::.:..||:|.|.|.:..|.|:|:.|||.|...:.|...|....|.|...
  Rat   131 TVTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSDRFGRKFVLKCALLQMAITETCVGFASN 195

  Fly   183 YFSFMVARYLLG-----IVGSAGAYIC-----GFVLTMELVGPTKRTVCGITFQAVFAGGIMLVA 237
            :|.:...|:|.|     |:.::...:.     .|:..|.::.|     |..:|      |.|::|
  Rat   196 FFIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAP-----CAGSF------GSMILA 249

  Fly   238 GWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRING---SGIP 299
            |......:...||:...:....||....||.||.|||.:..:..:.:..:.|...:||   ||..
  Rat   250 GLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGDN 314

  Fly   300 VDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFAN---SLVYYGLSLSAGKLY 361
            :..|......|::..| .|:.....|||.||.||.:   :|...|..   .|..:|:||....|.
  Rat   315 LTMEVVRTSMKRELEA-AKARPSPRDLFHTPILRKR---ICAMSFMRILFMLSIFGMSLHLQHLS 375

  Fly   362 GNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGS--TTSTAVVM 424
            .|..|:.|::........:...:|.:|:|||.....:|...|:|.:.|.::.|..  ...|.|.:
  Rat   376 SNIMLLQFVVSASSLLFSVIGPYVFNRMGRRITQMVVMTLRGICILTAVFVPQEMQILRITVVTL 440

  Fly   425 AGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVV 489
            || ...|.||.|...::.||.||.:|.:|:|:..|.......|.||..:|.|:.|.:|.:.:|..
  Rat   441 AG-AFSALSFGVNRLHTNELLPTTLRATAIGVIGMFGNSGFFLAPLFMILASYSPNLPWIFYGGF 504

  Fly   490 ALISGFWVMFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDP 543
            ::::||.|..||||.|||:|:.|.|     .|:.|      .:.||.  ..:||
  Rat   505 SILNGFTVFLLPETKNQPLPDCIHD-----IGNDW------EESRQE--MKEDP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	148/532 (28%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	104/388 (27%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	113/422 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010