DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and UST4r

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	563	Identity:	151/563 - (26%)
Similarity:	251/563 - (44%)	Gaps:	48/563 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            ::|:.::|..|::|.||....|.:.:....|::.....||:|.|||::..:||.::|.   |.|.
  Rat     4 QELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSD---NDSR 65

  Fly    73 IL-------AAIPLKPNGELESCLMF-DP--------------SSPGTNTTINCERYVYDTTYYK 115
            ||       .:|||..:..|:.|..| .|              :.|.|...:  :.:|||.:.:.
  Rat    66 ILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEPDTEPCV--DGWVYDRSNFH 128

  Fly   116 TSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFI 180
            ::...:||.||:.:.:.::.:..||:|.|.|.:..|.|:|:.|||.:..::.|...|......|.
  Rat   129 STTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYALLQMAITETCAGFA 193

  Fly   181 PEYFSFMVARYLLGIVGSAGAYICGFVLTM-ELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIP 244
            |..|.:...|:|.|:  |.........|.| |...|...|:..:......:.|.|::||......
  Rat   194 PNLFIYCSLRFLAGM--SLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSFGGMILAGLAFQFQ 256

  Fly   245 DRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRING---SGIPVDKEYYV 306
            :...||:...:....||....||.||.|||.:..:..:.:..:.|...|||   ||..:..|...
  Rat   257 NWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAHINGMKKSGDNITMEVVR 321

  Fly   307 QKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIM 371
            ...|::..| .|......|||.||.||.:...:........|...|:::....|..|..|:..::
  Rat   322 TSMKKELEA-AKMRPSPRDLFHTPILRKQIYILSFIRLLFILSGVGVAIHLQHLSNNIELLQILI 385

  Fly   372 GLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAVV-MAGKLLIAGSFA 435
            .:......:...|||:.:|||.....:|...|:..:.|.:..|...|...:: |..:.|.|.|:|
  Rat   386 SVSSILFSVIGHFVLNHIGRRITQMVIMFLRGISILTAIFAPQEMETLRFIMAMMAEGLAALSYA 450

  Fly   436 VIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFL 500
            ....::.||.||.:|.:|.|:..|...:...|.||..:|.|:.|.:|.:.:|..|::|||.|:.|
  Rat   451 ANSLHANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLASYSPNLPWIFYGGFAILSGFIVLLL 515

  Fly   501 PETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDP 543
            |||.|.|:|:...|.||     .|      ::.||.  ..:||
  Rat   516 PETKNNPLPDCTHDVEN-----DW------KESRQE--MKEDP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	141/521 (27%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	99/375 (26%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	108/411 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010