DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6126 and AgaP_AGAP005530

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_315530.4	Gene:	AgaP_AGAP005530 / 1276213	VectorBaseID:	AGAP005530	Length:	569	Species:	Anopheles gambiae

Alignment Length:	560	Identity:	164/560 - (29%)
Similarity:	261/560 - (46%)	Gaps:	58/560 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVDYVLEDLMGKLGEFGKYQFLQFFLQVL---SGLTAGMHMLSLVTVAAVPEHRCFI---EGVD 59
            |..|.:|:...|    ||.||  :..:.||   :......|..|.:.:||.|.|.|.:   :|.|
Mosquito     1 MDFDSILDMCDG----FGAYQ--KIIIGVLLFPATFPCAFHAYSQLFLAAKPNHWCKVPQLDGFD 59

  Fly    60 NS--------SLSVTPWNSSAI---LAAIPLKPNGELESCL-------MFDPSSPGTNTTINCER 106
            |.        |:...|::....   ..::.|:...|:.|.|       ..:..||....|.....
Mosquito    60 NHFTDLLKNISIPQLPYSDGTTGYSKCSMYLRNYSEIASHLRSAAGNVSLEQLSPPNGITSCRHG 124

  Fly   107 YVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQL 171
            :.||.:.:.::...|||.||||.:.......||.:....|.:..|.:.|..|||..|....:.|:
Mosquito   125 WSYDQSIFNSTVVTDWNLVCDRDFDTTTALMVFGVAGLIGNLGFGYMQDYWGRKLSFFLCLVVQV 189

  Fly   172 IIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLV 236
            ..|...|.:..|.|::|.|.::|:...| .....::|.:|||.|.:|..|.|.....::.|::|:
Mosquito   190 TAGAVGAAMWSYGSWLVTRIVVGLTVPA-ILSSPYMLAIELVEPKRRNFCTIISNIAYSVGLVLL 253

  Fly   237 AGWGALIPDRQW--LQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIP 299
            :  ..:..:|.|  |.:...|...:....:..:.||||||..:|:.::|..|:.|..|:||..|.
Mosquito   254 S--VIVYYERDWRSLSIAVSLPLLVLFLFYTLIPESPRWLAARGKYSQAQRILLKMARVNGKTID 316

  Fly   300 ------VD---KEYYVQKAKQQAAAEEKSSA-----GLSDLFRTPNLRMKTLNVCLCWFANSLVY 350
                  :|   |...::.|.:..|.:|.:::     ||..||..|.:|.||..|...|..|:.||
Mosquito   317 DGYRKLLDERIKALSLEDAPEHPATDETANSHAHEIGLRHLFDKPQMRRKTTFVAFIWLTNTSVY 381

  Fly   351 YGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG 415
            .|||..|..|.|:.....|:.||||.|:||.:...|:..|||.:..|.|:.|||.| ....|.||
Mosquito   382 VGLSYYAPALGGDEIFNFFLAGLVELPTYIVLWPSLNLFGRRGVLFTTMVIGGLAC-AFTIIPQG 445

  Fly   416 STTSTAVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPK 480
            .||:..:...||:.::.:|.|:...::|::|||:|    |||.....:.|.|.|::..|.::..|
Mosquito   446 RTTTLILYCIGKMGVSSAFVVVPLTASEIYPTVIR----GLGMSFCSVVGMLGPIVIPLMNYTGK 506

  Fly   481 ----IPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGE 516
                ||.|:.|:.....|...:|||||.|.|:|:::.|||
Mosquito   507 ENVAIPLVIMGLALTAGGIASLFLPETKNMPLPQTLADGE 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	156/538 (29%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	116/390 (30%)
AgaP_AGAP005530	XP_315530.4	2A0119	12..541	CDD:273328	158/542 (29%)
AgaP_AGAP005530	XP_315530.4	MFS	126..531	CDD:119392	125/412 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	4	3.920