Protein Alignment CG6126 and SLC22A9

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 152/567 - (26%)
• Similarity: 260/567 - (45%)
• Gaps: 50/567 - (8%)

  Fly     8 EDLMGKLGEFGKYQFLQ-FFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLS---VTPW 68
            :||:|..|:..::|.|| .||.:.:..|....||...| |.:|.|||::..:||.::|   ....
Human     4 QDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFT-AFIPGHRCWVHILDNDTVSDNDTGAL 67

  Fly    69 NSSAIL-AAIPLKPNGELESCLMF-------------DPSSPGTNTTINCERYVYDTTYYKTSRT 119
            :..|:| .:|||..|...|.|..|             .|::...:.....:.:|||...:.::..
Human    68 SQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSSTIV 132

  Fly   120 IDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYF 184
            .:|:.|||.:.:.::.:.|||.|:..|.:..|.|:|:.||:.|..|..|...|:|...|..|.:.
Human   133 TEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFL 197

  Fly   185 SFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAG-GIMLVAGWGALIPDRQW 248
            .:...|:|.||  :|.:.|...::.:......:....|||.....:| ..|.:||....|.|...
Human   198 IYCSLRFLSGI--AAMSLITNTIMLIAEWATHRFQAMGITLGMCPSGIAFMTLAGLAFAIRDWHI 260

  Fly   249 LQVIYGL-HGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDK---EYYVQKA 309
            ||::..: :..:||...|.| ||.|||.:..:..|.:..:.|....:|.....|.   |......
Human   261 LQLVVSVPYFVIFLTSSWLL-ESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTM 324

  Fly   310 KQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLV 374
            |::..|.:|....|.::...||:..:...:....|||.:.|:||:|....|..|.:|:..:.|.|
Human   325 KKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAV 389

  Fly   375 EFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMA---GKLLIAGSFAV 436
            ...:.....:.|..:.||:....||....:|.:...::.|...|...|:..   |...:|.:.|
Human   390 ILLANCVAPWALKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLA- 453

  Fly   437 IYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLP 501
             :.:..|:.||::|..|||:.:..|.::|||.||:.:|..:.|.:|.:::||...||||..:.||
Human   454 -FAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLP 517

  Fly   502 ETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDPEQMVP 548
            ||.|:|:.::|:|.:|..|.                  |.:|:|..|
Human   518 ETRNKPLFDTIQDEKNERKD------------------PREPKQEDP 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	141/520 (27%)
		MFS	130..501	CDD:119392	100/378 (26%)
SLC22A9	NP_543142.2	Sugar_tr	11..527	CDD:331684	141/521 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		8/37 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.010