Protein Alignment CG6126 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 178/642 - (27%)
• Similarity: 275/642 - (42%)
• Gaps: 130/642 - (20%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            |:|:.::|.||.:|.....|..|..:...:|.|..:.:||||.|||.:.|...:......|
Human     4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVW---- 64

  Fly    73 ILAAIPLKPNGELESCLMFDPSSPGTNTTINCER------------------YVYDTTYYKTSRT 119
            :.|.:|.:|:|.|.|||.|.......|||:..||                  :.||.:.:  |.|
Human    65 LEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEF--SST 127

  Fly   120 I---------------------------------------------------------------D 121
            |                                                               :
Human   128 IATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRESLGGLLSGME 192

  Fly   122 WNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSF 186
            |:.||:::.:.....|.|..||..|||..|.|:|:.||:.:...:.:..|::|:..|....|..|
Human   193 WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 257

  Fly   187 MVARYLLGIVGSAGAYICGFVLTMELVGPTK--------RTVCGITFQAVFAGGIMLVAGWGALI 243
            .:.|.|      .|:.:.||.:.:..:|..:        |||.|:.....:.||:||:|..|.||
Human   258 AITRTL------TGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLI 316

  Fly   244 PDRQWLQVIYGL---HGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYY 305
            .|.:||.:...|   .|.|.|   ||:.||.|||..||...||...:....|:||.  ||.::.:
Human   317 RDWRWLLLAVTLPCAPGILSL---WWVPESARWLLTQGHVKEAHRYLLHCARLNGR--PVCEDSF 376

  Fly   306 VQKAKQQAAAEEK--SSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLIL 368
            .|:|..:.||.|:  ......||||||.||..:|...:.||..:..||||||....|..|.|...
Human   377 SQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQ 441

  Fly   369 FIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQG-STTSTAVVMAGKLLIAG 432
            .:.|.||.||.:.:...:...|||...:..:||..|.......::.. .:.||.:.:.||.....
Human   442 LLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEA 506

  Fly   433 SFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWV 497
            :|...|.:::||:|||:|.:.|||.::..||.|:|.||..|||.....:|.:.:|.:||::....
Human   507 AFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTA 571

  Fly   498 MFLPETMNQPMPESIEDGENFGKGDTWFSQCAGRKKRQNSVYPDDPEQMVPLKNIES 554
            :.||||....:||:|:|.|              ||....|:    .|:.:|:|.:::
Human   572 LLLPETRQAQLPETIQDVE--------------RKSAPTSL----QEEEMPMKQVQN 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	165/589 (28%)
		MFS	130..501	CDD:119392	122/384 (32%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	166/590 (28%)
		MFS	206..563	CDD:119392	120/367 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S6248
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	7.000