DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and slc22a13

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	534	Identity:	187/534 - (35%)
Similarity:	272/534 - (50%)	Gaps:	37/534 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLMGKLGEFGKYQ-FLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTP--WNS 70
            :::..:||||::| .|...|.:||.|.| .||.|.|.:.....|||....:    |.:.|  ..:
Frog     6 EILKNVGEFGRFQKQLVVVLSLLSFLNA-FHMFSQVFMEIPVPHRCDSRWI----LLINPNLTEA 65

  Fly    71 SAILAAIPLKPNGELESCLMFDP--------SSPGTNTTINC-ERYVYDTTYYKTSRTIDWNFVC 126
            ..:...||....|:.|.|||:.|        ...|.|:|..| :.:.|||:..|::....::.||
Frog    66 ERLNYTIPRDGRGQYEQCLMYSPVQWDMESIEKFGLNSTGPCQDGWEYDTSEQKSTLVTQFDLVC 130

  Fly   127 DRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARY 191
            .||....|.|:|:|.|:..||:..|.|.|::||:.|...|.|.||:.|:..||.|.::.:...|:
Frog   131 HRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLVFGLSAAFAPHFYVYTAFRW 195

  Fly   192 LLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAG--WGALIPDRQW--LQVI 252
            ::| ...:|..|...||..|.||.::|....||....||.|:|.:||  :|.    |.|  ||::
Frog   196 VVG-TSMSGLMINNLVLGAEWVGSSRRACATITAHVCFAVGLMALAGVSYGI----RNWRLLQIV 255

  Fly   253 YGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEE 317
            ......|...:.|.|.||.|||..:|:..:||.::.|...:|...||.|..:...        ||
Frog   256 SSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLLFQFN--------EE 312

  Fly   318 KS--SAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYI 380
            ||  |..:.||||...||..||.:||.||.||||||||||:.|....:.||...:.|.||.|:.|
Frog   313 KSPKSGNMIDLFRNKTLRKLTLVMCLVWFVNSLVYYGLSLNVGSFGLDIYLTQLVFGAVEIPARI 377

  Fly   381 TIVFVLDRLGRR-SITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAGSFAVIYNYSAEL 444
            ..:|.:...||: |....|.|||.:|.|:.|.........|.:.:.||..||.||::.|.|:||:
Frog   378 GAMFAVQLFGRKPSQMFCLFLGGTVCLIITAIPRNLPIAITILAVIGKFSIASSFSICYIYAAEV 442

  Fly   445 FPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQPMP 509
            ||||:|.:.:||.||.||::|...|||:|||.:...||..::|...:|.|.....||||.|:.:.
Frog   443 FPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGPIIGGILCFLLPETRNKDLQ 507

  Fly   510 ESIEDGENFGKGDT 523
            :..:..|.....:|
Frog   508 DHTQQDEPIKSSNT 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	185/513 (36%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	140/377 (37%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	185/514 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm14089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930