DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6126 and LOC100490946

DIOPT Version :9

Sequence 1:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_031756488.1	Gene:	LOC100490946 / 100490946	-ID:	-	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	533	Identity:	146/533 - (27%)
Similarity:	245/533 - (45%)	Gaps:	56/533 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVDYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSV 65
            ||:..:.:|.:     |..:|.:...|........|.|....|..||||.:.|      .|::::
Frog     3 MALSVLDKDSL-----FSPFQAIMVTLLSAPLCFVGTHNFMPVFAAAVPPYNC------RSNMTM 56

  Fly    66 TPWNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCER-YVYDTTYYKTSRTIDWNFVCDRR 129
            .             :|....:.|..:..|.  :|:|..||. :.||.:.:.::...:|:.||||:
Frog    57 D-------------QPRYPEDPCTQYVSSL--SNSTKPCEEGWEYDHSIFTSTIISEWDLVCDRQ 106

  Fly   130 WMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLG 194
            .:..:.|:|:|.||..||...|.|||:.||:.:...|.|....:|:|||..|....:.:.|:|.|
Frog   107 TLKEVAQSVYMAGVLVGAAVYGALADRFGRRAMILCSLLQIAGMGIGVALSPNIIVYCLFRFLTG 171

  Fly   195 IVGSAGAYICGFVLTMELVGPTKRTVC------GITFQAVFAGGI-MLVAGWGALIPDRQWLQVI 252
             :|..|..|....|.||......|.:.      |:|..|:...|: ..:.||       :|||:.
Frog   172 -MGICGLIINDLGLAMEWTPRRYRPIVSMIQGYGLTCGAIILVGLAYAIRGW-------RWLQLT 228

  Fly   253 YGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRING--SGIPVDKEYYVQKAKQQAAA 315
            ..|...:|.....|:.||.|||.::..:.:|:..:.:..:|||  .|.|:..|......:....|
Frog   229 ASLPYFIFFLLMCWVPESARWLSLKKHSNQALANLNRVAKINGRKEGGPITLEMLKLDDQHSTKA 293

  Fly   316 EEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYI 380
            .......| ||||||.:|..||.:.|.||::|..::.::|...:...:.||...:....|.|..|
Frog   294 MTTKLTPL-DLFRTPTMRTITLILSLSWFSSSFGFFAIALDVDRFGLSLYLTQGVFAGSELPIRI 357

  Fly   381 TIVFVLDRLGRRSITSTLMLGGG--LCCIVAA----YIAQGSTTSTAVVMAGKLLIAGSFAVIYN 439
            ........:|||...|.|::..|  |.|.:|.    .:.|...|..|....|..::..     |.
Frog   358 LATITAFYIGRRLTISFLLIFAGTLLLCTMAVPKDMLLLQMILTVLAKASLGSCIVCS-----YL 417

  Fly   440 YSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETM 504
            |:||::|||:|.:.:|..:|..||...::||:.:...:...:|.|:|.|:.:|||..::.||||:
Frog   418 YTAEVYPTVLRQTGLGFTNMMMRLGAIISPLVMITRVYVSFLPMVIFAVMPIISGLPILLLPETL 482

  Fly   505 NQPMPESIEDGEN 517
            |.|:.:::|:.|:
Frog   483 NCPLMDTVEEVES 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	141/510 (28%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	109/385 (28%)
LOC100490946	XP_031756488.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010