Protein Alignment CG8925 and SLC22A6

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_004781.2
• Gene: SLC22A6 / 9356
• HGNCID: 10970
• Length: 563
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 59/321 - (18%)
• Similarity: 108/321 - (33%)
• Gaps: 92/321 - (28%)

  Fly   588 RDILKGLQYLHKSSI---------------GYHGHL---QASTCL-----IDINWV--------- 620
            |.:.||:...|::.:               ||:..|   ::|:.|     .|:|..
Human    69 RYVRKGIPLEHRARVWMAVSGAQARMDQSPGYYHRLLEGESSSSLDEAIRTDLNRTFPDNVMFRK 133

  Fly   621 -----LKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPPEHIREYDDSGKQPPRVVRG 680
                 |:.|||.|       |.|..:..|:     :.|.|.....|.     ..:|      :|.
Human   134 TADPCLQKTLYNV-------LLAYGLHNPD-----VGYCQCCAQKPG-----SSAG------LRS 175

  Fly   681 SPKGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNENHMPRITDDYRQENMLLEMCKE 745
            |..|..:..|.:..:....|:.:.|:.:       |:.:||.:.:.|.:......:.:|.|:.:.
Human   176 SLTGMNFIAGYLILITKNEEESFWLLDA-------LVGRILPDYYSPAMLGLKTDQEVLAELVRM 233

  Fly   746 CWDRNPDKRPTIKKLIESISTVYPLSKGNLVDQMIRMSEKYADELEQMVAIRTADLADAQMQTMR 810
                   |.|.:..|::....::.|    ||.:....  .:.|.|.....:|..|.
Human   234 -------KLPAVAALMDGHGVLWTL----LVSRWFIC--LFVDILPVETVLRIWDC--------- 276

  Fly   811 LLNEMLPASIAKDLKNGLIMPPRSYESATVMFVQICD-FNALMKRSSPEQVIAFLNDIYDQ 870
            |.||  .:.|...:...||...:.:.........||| |..:.|.....:..||:..|:.:
Human   277 LFNE--GSKIIFRVALTLIKQHQEFILEASSIPDICDKFKQITKGDFVTECHAFMQKIFSE 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	22/114 (19%)
SLC22A6	NP_004781.2	2A0119	11..515	CDD:273328	59/321 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..563