Protein Alignment CG8925 and Slc22a16

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 586
• Identity: 145/586 - (24%)
• Similarity: 245/586 - (41%)
• Gaps: 127/586 - (21%)

  Fly   141 NLDLL-----HTKLLERLLGCLTPWQSMWCA---LLSIFQAICTFHIFVYVFQIAPKDFWCARPE 197
            |::|:     |....:.:|..:..:||:.|.   |.|:|.:|...|              ..:|.
Mouse     5 NVELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEH--------------ACKPP 55

  Fly   198 NLMQM----SVSEWRNISQSSNGCLLLDV---------DYTQVTYENNQL-------INWPENAT 242
            .:::.    :||.||          |.|:         |:..|..::.::       ..|.||.:
Mouse    56 GMVRKAVFHNVSAWR----------LEDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTS 110

  Fly   243 DLGYR--------QCWHFEFSDVDGSAKTLVQEFDLVCGRD-ILSLVETCFLVGAAAGAVLSGWI 298
            .|||.        .|:.....|......:.|:.|:|||.:. ...:::...:.|...|::...::
Mouse   111 HLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYL 175

  Fly   299 SDRFGRRHTLMAFVTIQSVFGGILA-FSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWR 362
            |||||||..|.. .:|...|.||.: |......||..|..:..||....||.||.|:|::..|.|
Mouse   176 SDRFGRRMALWC-TSIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKAR 239

  Fly   363 TVIGI-LNILPVAISYVLSAGLAYLIRDWRHLQLAISWPWLIMLSI---------WFWLPESPRW 417
            |...| ||.. .||..:|.|..:||::.|        |.:.|:|.|         |. |||:|.|
Mouse   240 TWASIHLNTF-FAIGAMLVALASYLLKTW--------WLYQIILCIVTTPFILCCWM-LPETPFW 294

  Fly   418 LLAQGRLDELCGLIERAARMNGTSASLPSNYRKTLEAAVPRAVQSPPEATTSVESKAVEADAPDP 482
            ||::||..|..|.::..|..|.:|:   .:..:.|...|.|:....|.:...
Mouse   295 LLSEGRYKEAQGTVDTMAVWNKSSS---CDLVELLSLDVTRSHNKSPHSIRK------------- 343

  Fly   483 SASGHVNPLLVVFS----AKYWRTTCLTLVIWL-----TLIIIYFGLTLHLSNLGGNIYINSAVA 538
                  :.|..:|.    ||      :||::||     .|....||..:........:|:  .:.
Mouse   344 ------HRLADLFHNLDVAK------MTLIVWLDWFTANLGYYMFGKEVIRRKENEPLYL--LLV 394

  Fly   539 GTVEAIS-ICISILVVLKVGIRRSLIGYMLLPGLCCLATNLVSN--QTGVIALATIAKCLIGANN 600
            |.:|..: ||:.|. :.:||.|::::.::|:..|.|:...::.:  :|....:|.:.|.:|.:..
Mouse   395 GAMEIPAYICLCIW-LKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLVKSVISSVF 458

  Fly   601 AIIPTYTAMQYPTIVRNFGVGMGNLASGIALILVPFLWKLEHIDPLLPLNVMGVCGLI-GAVAIS 664
            |.|..|||..|||.||...||..|:.|.::.|.:||......:...||..:.|:..:: |.:::.
Mouse   459 AFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLK 523

  Fly   665 L 665
            |
Mouse   524 L 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	118/442 (27%)
Slc22a16	NP_081848.1	MFS_SLC22A16_CT2	118..525	CDD:340933	118/449 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649