Protein Alignment CG8925 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 134/552 - (24%)
• Similarity: 228/552 - (41%)
• Gaps: 93/552 - (16%)

  Fly   160 WQSMWCALLSIFQAICTFHIFVYVFQIAPKDFWCARPENLMQMSVSEWRNISQSSNGCLLLDVDY 224
            :|.....:|:|...:.:.|..:..|..|.....|:  .||:..|.||   ||.:.|
  Rat    16 FQIWMIVVLNILSMVSSLHDVIENFTAAIPAHHCS--VNLLDTSRSE---ISMAMN--------- 66

  Fly   225 TQVTYENNQLINWP---------------------------ENATDLGYRQC---WHFEFSDVDG 259
              :|.|....::.|                           .|:|:|....|   |.::.|..
  Rat    67 --LTTEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETEPCLDGWTYDHSVF-- 127

  Fly   260 SAKTLVQEFDLVCGRDILSL---VETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGI 321
             ..|:|.|:||||  |..|.   .:...|.|....|...|.|||||||:..||.......:.|..
  Rat   128 -TSTIVTEWDLVC--DFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPLLMYCSLAYGILGTC 189

  Fly   322 LAFSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGLAYL 386
            .||..:.:::..||.:...::.||.:...:||:|..|.:|...:.:|:.|..:.......||||:
  Rat   190 CAFVPNFSLYCVLRFLSSASASTVGMNCLILVLEETSVQWHATVIVLSGLFSSTGLAGLGGLAYV 254

  Fly   387 IRDWRHLQLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSNYRKT 451
            :.||..:||..:.|:.|...::.|:|||.|||:..|:.|:....::|.|.:||......:...:.
  Rat   255 LSDWHLIQLTSALPYFIFFILFCWVPESARWLMITGKTDQALKELQRIASINGKKDIAQNLTTED 319

  Fly   452 LEAAVPRAVQSPPEATTSVESKAVEADAPDPSASGHVNPLL--VVFSAKYWRTTCLTLVIWLTLI 514
            |.:.|...|.|      :|:..:::...        :||::  :|.        |.:.|::..|.
  Rat   320 LRSKVKEDVCS------TVKHFSIKDII--------INPMIRKIVL--------CYSSVLFAELF 362

  Fly   515 IIYFGLTLHLSNLGGNIYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLL-PGLCCLATNL 578
            .| |||.|.:..||.||::...:.|.::..|..::..::..|. ||.||.::|. .|.|...|..
  Rat   363 SI-FGLLLDVHMLGKNIFVTQILLGVIDIPSKSLTYFILRNVR-RRPLIAFLLFATGGCITITMF 425

  Fly   579 VSNQTGVIALATIA------KCLIGANNAIIPTYTAMQYPTIVRNFGVGMGNLASGI-ALILVPF 636
            :|....|:.||...      ...|..|.|.....:.:...:.:....:.:..|||.: ||.||..
  Rat   426 LSEDMYVLRLAIFILGKGCFAAFISINTAYCNELSPVPLRSTLNGIYISVARLASVLSALTLVTR 490

  Fly   637 LWKLEHIDPLLPLNVMGVCGLIGAVAISLMKD 668
            .:.:     |||:...||..::..:.|..:.:
  Rat   491 KYFV-----LLPMIFCGVLPIVATINIYFLPE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	113/432 (26%)
Slc22a22	NP_001013969.1	MFS_OAT	109..516	CDD:340932	115/440 (26%)