Protein Alignment CG8925 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 582
• Identity: 135/582 - (23%)
• Similarity: 227/582 - (39%)
• Gaps: 135/582 - (23%)

  Fly   167 LLSIFQAICTFHIFVYVFQIAPKDFWCA----------------RPENLMQMSVSEWRNISQSSN 215
            ||:|...:.:.|..:..|..|.....|:                ..|:||::|:....|  |...
Mouse    23 LLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMNLTTEDLMKVSIPMGPN--QKPE 85

  Fly   216 GCLLLDVDYTQVTYENNQLINWPENATDLGYRQC---WHF------------------------- 252
            .|...  .|||..:.::.:..:  |:|:|....|   |.:
Mouse    86 QCRRF--RYTQWQFLDSNISTF--NSTELETEPCLDGWTYDHSVFTSTIVTEGLSPPQPWDSDQY 146

  Fly   253 -----EFSDVDGSAKTLVQEFDLVCGRDILSL---VETCFLVGAAAGAVLSGWISDRFGRRHTLM 309
                 |.|..:...|:.|:.:||||  |..|.   .:...|.|......|||.|||||||:..||
Mouse   147 YHTKHEISPCEEGLKSSVKVWDLVC--DFQSFKYYAQATSLAGHLVSCPLSGIISDRFGRKPLLM 209

  Fly   310 AFVTIQSVFGGILAFSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVA 374
            .........|...||:.:.:::..||.::.....|:.:.|.:||:|..|.:|...|.:|:.|..:
Mouse   210 YCSLAYGAVGTYCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEEASVQWHPTIIVLSGLFNS 274

  Fly   375 ISYVLSAGLAYLIRDWRHLQLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNG 439
            |...:..||||:|.||..||||.:.|:.|...::.|:|||.|||:..|:.|:....::|.|.:||
Mouse   275 IGQGVLGGLAYVISDWHLLQLAYALPFFIFFVLFCWVPESVRWLIITGKTDQAWKELQRIASING 339

  Fly   440 --------TSASLPSNYRKTLEAAVPRAVQSPPEATTSVESKAVEADAPDPSASG--------HV 488
                    |:..|.|..:|                              |.:::|        .:
Mouse   340 KKGIAQNLTTEDLRSKLKK------------------------------DVNSTGKLFRIKDIFI 374

  Fly   489 NPLL--VVFSAKYWRTTCLTLVIWLTLIIIYFGLTLHLSNLGGNIYINSAVAGTVEAISICISIL 551
            |||:  :|.|         ...:....:..:.||.|.:..||.|:::.....|.::..|..::..
Mouse   375 NPLIRKIVLS---------NSSLLFAELFSFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYF 430

  Fly   552 VVLKVGIRRSLIGYMLL-PGLCCLATNLVSNQTGVI--ALATIAKCLIGANNAIIPTYTAMQYPT 613
            .:..|. ||.||.::|| .|.|...|..:|.:..|:  .:..:.|....|...|..||.....|.
Mouse   431 TIRNVS-RRPLIAFLLLTTGSCITITIFISEEMYVLRTIIFILGKGCFAAFTCISTTYINELSPV 494

  Fly   614 IVRNFGVGMGNLASGIALILVPFLWKLEHID-------PLLPLNVMGVCGLIGAVAISLMKD 668
            .:|       :..:|:.|.:|.....|..:.       ..||:.:.||..::..::|..:.:
Mouse   495 ELR-------STLNGVFLAVVRLAGVLSALTLATRKYFVYLPMILYGVLPIVATISILFLPE 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	115/480 (24%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	117/488 (24%)