Protein Alignment CG8925 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 474
• Identity: 134/474 - (28%)
• Similarity: 230/474 - (48%)
• Gaps: 44/474 - (9%)

  Fly   203 SVSEWRNISQSSNGCLLLDVDYTQVTYE-NNQLINWPENATDLGYRQCWHFEFSDVDGSAKTLVQ 266
            |..|...:||    |:..:||:.|.|.: .:.|.:...|.:.|....|.|....|..||  ::|.
Mouse    79 SAGEVSFLSQ----CMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGS--SIVT 137

  Fly   267 EFDLVCGRD-ILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTSVAM 330
            ||:|||... :|.|.::...||...|||..|:::|||||:..|:..:.|.::.|.::|.|.:.|.
Mouse   138 EFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISPNYAW 202

  Fly   331 FMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGLAYLIRDWRHLQL 395
            .:..|.:.|..|....::.::|:.|.|...:|..:||...:...:..::.||:||.:.:||.||.
Mouse   203 MLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQF 267

  Fly   396 AISWPWLIMLSIWFW-LPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSNYRKTLEAAVPRA 459
            |::.|....| ::|| :|||||||::|.:..:...:|:..|:.||.|              ||.:
Mouse   268 AVTLPNFCFL-LYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKS--------------VPVS 317

  Fly   460 VQSPPEATTSVESKAVEADAPDPSASGHVNP--LLVVFSAKYWRTTCLTLVIWLTLIIIYFGLTL 522
            :||    .|:.|...::           :||  |.:|.:.:..:.|.:.:..|.|..::|.||.:
Mouse   318 LQS----LTADEDTGMK-----------LNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIM 367

  Fly   523 HLSNLGGNIYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLLPGLCCLATNLVSN--QTGV 585
            |:...|.|||::...:..||..:..|.||.:.::|.|.......::.|..|||:..:.:  |...
Mouse   368 HMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDLQWLK 432

  Fly   586 IALATIAKCLIGANNAIIPTYTAMQYPTIVRNFGVGMGNLASGIALILVPFL-WKLEHIDPLLPL 649
            |.:|.:.:..|.....::....|..|||.:||..|.:.:....|..|:.||| ::|..|....||
Mouse   433 ITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPL 497

  Fly   650 NVMGVCGLIGAVAISLMKD 668
            .|..|.||:....:.|:.:
Mouse   498 VVFAVVGLVAGGLVLLLPE 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	121/423 (29%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	134/474 (28%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		3/3 (100%)