Protein Alignment CG8925 and F45E10.2

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001022174.1
• Gene: F45E10.2 / 185801
• WormBaseID: WBGene00009729
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 137/602 - (22%)
• Similarity: 254/602 - (42%)
• Gaps: 131/602 - (21%)

  Fly   109 LPTTFHLFMFVFQLTDVRS--GEA-SPMLSDG-----------NMENLDLLHTKL-LERL---LG 155
            :|.|....:..:..:||.:  .|| :|::..|           .:|.:|:.:.|: ||.:   ||
 Worm    12 IPQTAQTTITSYCSSDVINSLNEAMNPLIEQGLKDIGTKQEAHYVEEVDVRNDKIKLESIFEGLG 76

  Fly   156 CLTPWQSMWCALLSIFQAICTFHIFVYVFQIAPKDFWCARPENLMQMSVSEWRNISQSSN----- 215
            ....:|.:...|:.|..|..:.|:..:.|.::|.                  |.|...:|
 Worm    77 SFGRFQQIQFILICIPIAFVSMHVMSWTFVVSPA------------------RKICNETNETRID 123

  Fly   216 GCLLLDVDYTQVTYENNQLINWPENATDLGYRQCWHFEFSDVDGSAKTLVQEFDLVCGRDILSLV 280
            ||                        .:|.|.....:|....:|..:..||
 Worm   124 GC------------------------EELAYSASDRWEMDGDNGWIRATVQ-------------- 150

  Fly   281 ETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTSVAMFMSLRVIIGFASMTV 345
             ..:.:|...|:...|.::|:.||:..|...:.:|.|...:|..:.:..::..|:...||....:
 Worm   151 -AVYFIGQMIGSFTCGVMADKIGRKKVLFWCLVLQVVCALLLIVAPTWWIYAILKAGTGFTQPGI 214

  Fly   346 TVVSFVLVVELVSGKWRTVIGIL-NILPVAISYVLSAGLAYLIRDWRHLQLAISWPWLIMLSIWF 409
            ..|:.||.:|||..|:|:.|.:: |:..| |..||.|.:||.|.|:|.|..:|:.|.||.::.::
 Worm   215 YGVAVVLGIELVGKKYRSFIAVIANVFGV-IGGVLLAVMAYFIVDYRLLHASIAIPSLIFITYYW 278

  Fly   410 WLPESPRWLLAQGRLDE----LCGLIERAARMNGTSASLPSNYRKTLEAAVPRAVQSPPEATTSV 470
            .:.||.|||::|.:.|:    ||      |..|....::|.|:.:.:|
 Worm   279 MIHESARWLVSQEKYDDANVVLC------ATANWNKKTIPKNWAEKIE----------------- 320

  Fly   471 ESKAVEADAPDPSASGHVNPLLVVFSAKYWRTTCLTLVIWLTLIIIYFGLTLHLSNLGGNIYINS 535
              |.::..|.....|..|..|  :.:.:..:.|....|:|....::|:|||:.....||::::..
 Worm   321 --KKMDVTATKKKDSFGVFDL--IRTPQMRKRTIANFVMWPVTTMMYYGLTMRSDVGGGSLFVTF 381

  Fly   536 AVAGTVEAISICISILVVLKVGIRRSLIGYMLLPGLCCLAT----NLVSNQTGVIALATIAKCLI 596
            ..:..:|..::.|..|::.::|.|....|.:...|:..||:    :|:.:|..||.| .:||..:
 Worm   382 VTSQLMELPAVIIVALLIDRLGRRIMYSGAIFTAGMLLLASWLTHDLIPSQYAVIML-MVAKGAV 445

  Fly   597 GANNAIIPTYTAMQYPTIVRNFGVG-------MGNL-ASGIALILVPFLWKLEHIDPLLPLNVMG 653
            .....::.|||:..:||::||..||       .|.: ||.||..||.   :...|..::|..::.
 Worm   446 SVAYTVMYTYTSELFPTVIRNTAVGCCSTIARFGAISASFIAFFLVD---RFGRIVMIIPFTILA 507

  Fly   654 VCGLIGAVAISLMKDVV 670
            :|..|  |:.:::.:.|
 Worm   508 LCASI--VSWTMLPETV 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	107/433 (25%)
F45E10.2	NP_001022174.1	MFS_SLC22	121..518	CDD:340875	111/469 (24%)