Protein Alignment CG8925 and K05F1.6

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001342018.1
• Gene: K05F1.6 / 173977
• WormBaseID: WBGene00019408
• Length: 858
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 165/697 - (23%)
• Similarity: 300/697 - (43%)
• Gaps: 130/697 - (18%)

  Fly    44 PEISVIALDFRRYSEDLKKPPSAEQTEQPPSRDLSQDEDSDVISNFLGHYTRWSFLWTLLLCLFQ 108
            |.:.|:|.:.|..|..:...|....:..|....::..||.::..:.:..|.|..          .
 Worm   109 PHMRVVADEMRNTSASVTAEPEPSVSHAPSVLTVTAPEDRNMYQSDISMYGRQG----------H 163

  Fly   109 LPTTFHLFMFVFQLTDVRS--GEASPMLSDGNMEN---------LDLLHTKLLERLLGCLTPWQS 162
            .|:        |...::|.  .:...:..|.|.:.         :|.  ..:|..:.||  .|..
 Worm   164 KPS--------FSTREIREQHQKVQQIYRDVNKKERKEGKPTDPIDF--EGILNIIGGC--RWWQ 216

  Fly   163 MWCALLSIFQAI--CTFHIFVYVFQIAPKDFWCARP----ENLMQMS--------VSEWRNIS-- 211
            :|..:|...|.|  ..|::.| |:.:...:|.|..|    .|...:|        |.:.:|||
 Worm   217 IWIYVLIALQQIPHAMFNLNV-VYMMYDPEFQCMVPGFNDTNDTTISSHGPYLWGVDDIKNISFV 280

  Fly   212 ---QSSNGCLLLDVDYTQVTYENN-----QLINWP-ENATDLGYR--------QCWHFEFSDVDG 259
               .:|:|....|..|   .||.:     ||...| |.|....::        |.:|||   .|.
 Worm   281 FPNANSDGAYQRDSCY---FYERSEERYRQLRRMPLETAMSEAWKDVAPKKKCQAYHFE---KDV 339

  Fly   260 SAKTLVQEFDLVC------GRDILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVF 318
            ..:|:|.:|:|||      |.     ....:.:|...|.||.|..||:.||:.|::.|..:.|:.
 Worm   340 MVETIVTDFNLVCDSWFAKGH-----AHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSML 399

  Fly   319 GGILAFSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGL 383
            |..|.|:....||:.:|::....:....:.::.|.:|:...|:|.::|.:...|.|:.|.|.|.:
 Worm   400 GVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALI 464

  Fly   384 AYLIRDWRHLQLAISWPWLIMLSIWF--WLPESPRWLLAQGRLDELCGLIERAAR-----MNGTS 441
            |||.:.|:.:|:..:  .|..:||.|  .:|||||||:.|.|:.|...:|.:|.|     .|..:
 Worm   465 AYLTKSWKTIQVIAA--GLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCT 527

  Fly   442 ASLPSNYRKTLEAAVPRAVQSPPEATTSVESKAVEADAPDPSASGHVNPLLVVFSAKYWR-TTCL 505
            .|...|....||....|            |.|.      :....|.:. .|.:|:.|..| .|..
 Worm   528 TSKCGNLPSDLELVSHR------------ERKL------NKKNGGKIG-FLDLFTMKELRYRTIS 573

  Fly   506 TLVIWLTLIIIYFGLTLHLSN--------LGGNIYINSAVAGTVEAISICISILVVLKVGIRRSL 562
            ..::::...::|:||.:.||:        ..|..::|:.:||.:| |....:.:.::::|.:::|
 Worm   574 VCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIE-IPTLFACVWMMQLGRKKAL 637

  Fly   563 IGYMLLPGLCCLATNLVSNQTG--VIALATI--AKCLI-GANNAIIPTYTAMQYPTIVRNFGVGM 622
            :..::..||..:.. ::|..:|  ::|||.:  .|..: ||.| |:..:|:..|||:|||..||:
 Worm   638 MLTLITSGLFIIVA-MLSMVSGHYMLALAFMYFGKIAVQGAFN-ILYIFTSELYPTVVRNTAVGV 700

  Fly   623 GNLASGIALILVPFLWKLEHID-PLLPLNVMGVCGLIGAVAISLMKD 668
            .::.:.....|..::..|.:|. |::|:.:..|..|...:.:.::.:
 Worm   701 TSMVARFGSGLSSYIALLSNISLPIVPMIIFAVFSLFAGMLVFVLPE 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	116/444 (26%)
K05F1.6	NP_001342018.1	MFS_SLC22	333..746	CDD:340875	116/444 (26%)