Protein Alignment CG8925 and SLC22A31

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 102/400 - (25%)
• Similarity: 166/400 - (41%)
• Gaps: 94/400 - (23%)

  Fly   264 LVQEFDLVCGRD-ILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTS 327
            |.|.::||||.. .:.|.:...|:|...|.|:.|...||||||...:|.:.:.:..|...|.:.|
Human     5 LSQNWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAAS 69

  Fly   328 VAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWR----------TVIGILNILPVAISYVLSAG 382
            ....:.||::.|.......:..::..:||.....|          :|:|.| :||         |
Human    70 FPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTL-LLP---------G 124

  Fly   383 LAYLIRDWRHLQ-LAISWPWLIMLSIWFW-----LPESPRWLLAQGRLDELCGLIERAARMNGTS 441
            ||.|::|||.|| |......|::|   ||     .||||.||||.|::.....::.|.|..:|..
Human   125 LAALVQDWRLLQGLGALMSGLLLL---FWGFPALFPESPCWLLATGQVARARKILWRFAEASGVG 186

  Fly   442 ASLPSNYRKTLEAAVPRAVQSPPEATTSVESKAVEADAPDPSASGHVNPLLVVFSAKYWRTTCLT 506
               |.:  .:||           |.:.:.|...:.|.:|.|.   :.:||.::.:...||.
Human   187 ---PGD--SSLE-----------ENSLATELTMLSARSPQPR---YHSPLGLLRTRVTWRN---- 228

  Fly   507 LVIWLTLIIIYFGLTLHLSNL-GGNI--YINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLL 568
                        ||.|..|:| ||.|  ....::|..|..    ..:...|:.|:..:.:.::||
Human   229 ------------GLILGFSSLVGGGIRASFRRSLAPQVPT----FYLPYFLEAGLEAAALVFLLL 277

  Fly   569 PGLCC------LATNLVSNQTGVIALATIAKCLIG---------------ANNAIIPTYTAMQYP 612
            ...||      |...:|:....::.||. |:.|.|               |.:|:...:.|..:|
Human   278 TADCCGRRPVLLLGTMVTGLASLLLLAG-AQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFP 341

  Fly   613 TIVRNFGVGM 622
            |::|..|:|:
Human   342 TVIRGAGLGL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	102/399 (26%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:475125	100/395 (25%)