Protein Alignment CG8925 and slc22a2

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_002933908.1
• Gene: slc22a2 / 100487774
• XenbaseID: XB-GENE-965056
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 141/549 - (25%)
• Similarity: 253/549 - (46%)
• Gaps: 75/549 - (13%)

  Fly   148 KLLERLLGCLTPWQS----MWCALLSIFQAICTFHIFVYVFQIAPKDFWCA-----RPENLMQMS 203
            :|||. :|....:|.    :.|.:..:|..|   ::.:......| |:.|.     .|.|
 Frog     6 ELLEH-IGEFDAFQKQIFILLCFISVVFSPI---YVGIVFLGFVP-DYRCVSAGIPEPSN----- 60

  Fly   204 VSEWRNISQSSNG---------CLLLDVDY--TQVTYENNQLINWPENATD-LGYRQC---WHFE 253
            ..||.......||         |...|||:  |.:...|:.|     |.|. |....|   |
 Frog    61 ECEWTLNYTGPNGSTDSLYMSQCYQYDVDWNSTSLNCTNSSL-----NITSKLPITNCKDGW--- 117

  Fly   254 FSDVDGSAKTLVQEFDLVCGRD-ILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSV 317
              |.:.:..:||.||:||||.. .|...::|..:|...|.::||:|:|||||:..|::.:.|..:
 Frog   118 --DYNTTGSSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIADRFGRKPFLISSILITGI 180

  Fly   318 FGGILAFSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAG 382
            ||.::||:.:..:.::.|.|.||.|....:..::||.|.|..:.|..:||:......:..:|.:|
 Frog   181 FGILMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSG 245

  Fly   383 LAYLIRDWRHLQLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSN 447
            :||::..||.||:.::.|:...|:.::.:|||||||::|.|..|...:|...|:.||
 Frog   246 VAYVLPHWRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNG-------- 302

  Fly   448 YRKTLEAAVPRAVQSPPEATTSVESKAVEADAPDPSASGHVNPLLVVFSAKYWRTTCLTLVIWLT 512
                  ..||..::|     .:.:.:|.|...|        :.|.:|.:.:..:.|.:.:.||.|
 Frog   303 ------KMVPDFLES-----LTADEEAGEKQVP--------SFLDLVRTPQIRKHTLILMYIWFT 348

  Fly   513 LIIIYFGLTLHLSNLGGNIYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLLPGLCCLATN 577
            ..::|.|..:|:.:...|||.:..::..||..|..:.|:.|.:||.|...:...::.|:.||.|.
 Frog   349 CAVVYQGSIMHMGSTAENIYFDFFISALVEFPSAILIIVTVDRVGRRYPWLVCCIITGITCLITA 413

  Fly   578 LVSNQTG--VIALATIAKCLIGANNAIIPTYTAMQYPTIVRNFGVGMGNLASGIALILVPFL-WK 639
            .:.:...  :|.|:.:::..|..:..::....|..|||.:||.|:.:.:....:..::.||: ::
 Frog   414 FIPHGYSWLIITLSCVSRMGITVSYEMVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIVYR 478

  Fly   640 LEHIDPLLPLNVMGVCGLIGAVAISLMKD 668
            |..|...|||.|..|...:..:.:..:.:
 Frog   479 LAAIWQELPLIVFAVLATVSGILVYFLPE 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	114/423 (27%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	138/542 (25%)