Protein Alignment CG8925 and slc22a6

DIOPT Version :10

• Sequence 1: NP_650526.1
• Gene: CG8925 / 41963
• FlyBaseID: FBgn0038404
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_002937540.1
• Gene: slc22a6 / 100487511
• XenbaseID: XB-GENE-5842250
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 533
• Identity: 135/533 - (25%)
• Similarity: 239/533 - (44%)
• Gaps: 52/533 - (9%)

  Fly   148 KLLERLLGCLTPWQSMWCALLSIFQAICTFHIFVYVFQIAPKDFWCARPENLMQMSVS------- 205
            ::||. :|.:..:|.:...|||:       .:|:.......::|..|.|.:..|::.|
 Frog     5 EILES-IGGMGRYQVIHVVLLSL-------PVFMLASHNLMQNFTAAIPRHRCQINGSFEETNFT 61

  Fly   206 -EWRN--ISQSSNGCLLLDVDYTQVTYENNQLINWPENATDLGYRQC---WHFEFSDVDGSAKTL 264
             .|..  :.....|.....:.||...| :..:.|:.:|..:|....|   |.::.|:.   |.|:
 Frog    62 GPWLRALVPMKPTGEFSKCLRYTTPQY-HLLMDNFTQNVDELETETCVDGWVYDHSEF---ASTI 122

  Fly   265 VQEFDLVCG-RDILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQ-SVFGGILAFSTS 327
            :.::||||. |.:..:.::.::.|...|:|:.|.:||:|||| .|..:..:| ||.|...|||.:
 Frog   123 ITQWDLVCNHRRMRQVAQSIYMAGVLVGSVVFGGLSDKFGRR-PLNIWSNLQMSVTGICAAFSPN 186

  Fly   328 VAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGLAYLIRDWRH 392
            ...:...|.:.|.|...:.:.|:.|:||.:....|............:..::..|||::||||..
 Frog   187 YIWYCIFRFLTGTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHW 251

  Fly   393 LQLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSNYRKTLEAAVP 457
            ||||.|.|:.......:|:|||.|||:..|:.:..|..:::.|::||...:......:.|::::.
 Frog   252 LQLAASLPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQ 316

  Fly   458 RAVQSPPEATTSVESKAVEADAPDPSASGHVNPLLVVFSAKYWRTTCLTLVIWLTLIIIYFGLTL 522
            |.:.:...:|.||                    |.:|.:....|.:......|.:....|:||.|
 Frog   317 REISASKHSTYSV--------------------LDLVRTPVVRRISFCISCTWFSTSFAYYGLAL 361

  Fly   523 HLSNLGGNIYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLLPGLCCLATNLVSN--QTGV 585
            .|.:.|.:|||...:.|||:..:...|..|:..:|.|......::|.|:..|....|..  ||..
 Frog   362 DLQSFGVSIYIIQIIFGTVDIPAKFFSYFVMTYIGRRVLQALTLILAGIAILVNICVPQDYQTVR 426

  Fly   586 IALATIAK-CLIGANNAIIPTYTAMQYPTIVRNFGVGMGNLASGIALILVPFLWKLEHIDPLLPL 649
            .::|...| ||..:.|.:. .||...|||::|..|:|:|.:.:.:..|:.|.......|...|||
 Frog   427 TSMAVFGKGCLAASFNCLF-LYTGELYPTVIRQSGMGLGTMMARLGGIIAPLAQMTGDIYHSLPL 490

  Fly   650 NVMGVCGLIGAVA 662
            .:.|...::..:|
 Frog   491 IIFGCLPILSGIA 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8925	NP_650526.1	MFS_SLC22	249..666	CDD:340875	114/422 (27%)
slc22a6	XP_002937540.1	MFS_SLC22A6_OAT1_like	102..508	CDD:341004	115/427 (27%)