Protein Alignment CG6006 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 144/555 - (25%)
• Similarity: 265/555 - (47%)
• Gaps: 65/555 - (11%)

  Fly    87 DLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANK-DFWCQRP--------AQLQHMPVATW 142
            |.:|.:|.:|   ..|::|..:|:   |.|:.:..|:. .|..|:|        |...|:..|..
Human   138 DAVGEFGTFQ---QRLVALTFIPS---IMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLSKAEQ 196

  Fly   143 RNL------SGSVDNCRRWEGIDWSQVS------NET-TLPSDWKTPAEMDKKLVACEKWEYETN 194
            .||      :||...|..:..:.|:..|      |:| |....|..|....:.|:
Human   197 LNLTIPQAPNGSFLTCFMYLPVPWNLDSIIQFGLNDTDTCQDGWIYPDAKKRSLI---------- 251

  Fly   195 DNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLW 259
                    :::||||..|..|:.|::.|:.|:..|.:|...::||.||...:.:|.:...|||..
Human   252 --------NEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFG 308

  Fly   260 LYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYL 324
            ....:||.|||..|..:....|....|.:.||.|::.|:.|..|.:.......:..::::|:||.
Human   309 TAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHCFFAVGAVLLTGIAYS 373

  Fly   325 TQDYQRLQLCIGIPGI-FLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADY--QL 386
            ...:|.|.|..||..| |:.::| ::|||||||::||::.|.::::..||..|.:.:|::.  :|
Human   374 LPHWQLLFLVGGILVIPFISYIW-ILPESPRWLMMKGKVKEAKQVLCYAASVNKKTIPSNLLDEL 437

  Fly   387 TPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEI 451
            ..|.::.:...|....::..|.::::...|:|||::..|:.:.|.|...|.:|:....:..::|:
Human   438 QLPRKKVTRASVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEV 502

  Fly   452 PAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLK-------------ITFLMM 503
            ||....::::.::|:||....||:.|.:.|..........|.|.||             |..||:
Human   503 PARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLML 567

  Fly   504 GKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWS 568
            .:|:::|..|:..:|||||.||.:|..|:|..::|:....||:  |:::::....|.:.|....:
Human   568 REFSLAATVTVFFLYTAELLPTVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLA 630

  Fly   569 IFGGFVVLFLPETAVRQKTDNQGGSSANASAAKQV 603
            |....:...||||..:..:::...||...:..|.:
Human   631 IVAFSLSSLLPETRDQPLSESLNHSSQIRNKVKDM 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	138/528 (26%)
		MFS	222..579	CDD:119392	101/372 (27%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	140/535 (26%)
		MFS	270..641	CDD:119392	101/373 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020