Protein Alignment CG6006 and TPO1

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_013072.1
• Gene: TPO1 / 850631
• SGDID: S000003951
• Length: 586
• Species: Saccharomyces cerevisiae
• Alignment Length: 526
• Identity: 119/526 - (22%)
• Similarity: 193/526 - (36%)
• Gaps: 168/526 - (31%)

  Fly   145 LSGSVDNCRRWEGIDWSQVS-------------------------NETTLPSDWKTPAEMDKK-- 182
            |:|||:...|.| :|::..:                         |:...|.:|    .|.||
Yeast    88 LTGSVNEPDRVE-VDYTNCAPMGGDRPYPPSLPSRDLYEVTFDGPNDPLHPFNW----PMKKKVL 147

  Fly   183 --LVACEKWEYETNDNV-----GNTWTSQWDLVCEKEHLKNVAEM----FFLLGVATGGIISGYL 236
              ||.|       .|::     .:.:.|....:||..|:..|..:    .|:||.|...:|...|
Yeast   148 LCLVLC-------LDSIAIAMCSSIFASAVPQICEIYHVIEVVAILGITLFVLGFAASPVIYAPL 205

  Fly   237 SDKFGRKTMLFISAV--------------LQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSG 287
            |:.:|||.:|.:||.              |||||     ||..|      ...:|...::|..:.
Yeast   206 SELYGRKGVLVLSAFGFALFQFAVATAENLQTIF-----ICRFF------GGFIGAAPMAVVPAA 259

  Fly   288 LILAIE-YVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQ--DYQRLQLCIGIPGIFLCF----- 344
            .....: .|.||...:..: .:|..||...::.  :|:.|  .::.|:..:|      ||
Yeast   260 FADMFDTNVRGKAIALFSL-GVFVGPILSPVMG--SYIAQRTTWRWLEYVVG------CFASAVF 315

  Fly   345 ----LWFVVPESPRWLLVKGRIDEVRRI-----IEAAAKFNGRQLPADYQLTPPTQESSTQDVTY 400
                |:|.....|..|:.|.:  ::|:.     |.||.:      ..:..:....|::.|:.:..
Yeast   316 VAIVLFFEETHHPTILVNKAK--QMRKQSNNWGIHAAHE------DVELSIKDIVQKTVTRPIIM 372

  Fly   401 LFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVE-IPAIAVAMYIITKV 464
            ||....|..::|        .|...|||:          ||      |:| .|.:.|..|..|:.
Yeast   373 LFVEPLLLFVTI--------YNSFVYGIL----------YL------LLEAYPLVFVEGYGFTEN 413

  Fly   465 GKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGK-------FTISAGNTIMPV----- 517
            | :..:.|.:|  |:..|.|.|  .:.|..:|| .....||       :.:....|:.|:
Yeast   414 G-ELPYIALII--GMMVCAAFI--WYMDNDYLK-RCRAKGKLVPEARLYAMVIAGTVFPIGILWF 472

  Fly   518 -YTAELYPTPIRNV--GVGACNVAAGLALILTPYLSLLNKIEGHLLM--------TLLTAWSIFG 571
             :|. .||..|..:  .||...:..||..|..|.|:.:  ||.:||:        |.:.  |.||
Yeast   473 CWTG-YYPHKIHWMVPTVGGAFIGFGLMGIFLPCLNYI--IESYLLLAASAVAANTFMR--SAFG 532

  Fly   572 GFVVLF 577
            ....||
Yeast   533 ACFPLF 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	103/453 (23%)
TPO1	NP_013072.1	MFS_Tpo1_MDR_like	156..577	CDD:340881	102/446 (23%)