DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and OCT2

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_178054.1	Gene:	OCT2 / 844274	AraportID:	AT1G79360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	136/558 - (24%)
Similarity:	229/558 - (41%)	Gaps:	97/558 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 ATPQSPAAAVSGLDPADDEDETDVIGDLMGHYGKWQLLMTVLLS---LFQVPNTFHISSSIYQAA 122
            |.|..|....|........|:|  |...:|.:|..|.|...|:|   :|....||   .|::..:
plant     2 AEPTQPLLTDSNSSSPRSLDDT--IESYIGSFGWAQFLQAALVSFSGVFDAQQTF---ISVFTDS 61

  Fly   123 NKDFWCQRPAQLQHMPVATWRNLSGSVDNCRRWEGIDWSQVSNETTLP-SDWKTPAEMDKKLVAC 186
            .                .||        :|.....|....:||...|| :.|
plant    62 E----------------PTW--------HCTDSNSICHESISNICILPKTAW------------- 89

  Fly   187 EKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSD-KFGRKTMLFISA 250
             .|:|..:.:|    .|:|.|.|....:|.:.|..|.:|...||::...|:| ..|||.|||:|.
plant    90 -SWDYSPHVSV----ISEWGLQCAGSFVKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSC 149

  Fly   251 VLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISY 315
            ::..|..:......:..:|..||.:.|....::....|:|:.|.|..|||...|:.:.|...:.:
plant   150 LVMAISTMLTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTELVGKKWRGRVGIMSFFGFMLGF 214

  Fly   316 MIISGLAYLTQ--DYQRLQLCIGIPGIFLCFL-WFVVPESPRWLLVKGRIDEVRRIIEAAAKF-- 375
            :.:..:||:.:  .::.|.....||.|..|.| .|.|.||||||.|:||.:|...|::..|..
plant   215 LSLPLMAYMNRGSSWRILYAWTSIPTIIYCVLVRFFVCESPRWLFVRGRREEAISILKRVASIPS 279

  Fly   376 ----NGRQLPADYQLTP--PTQESSTQDVTYLFRSS--------YLRRISICFFCIWFTMNLVYY 426
                :|..:...:...|  ..:|..:.:|. :|.:.        .|:|:| ....|.|.:.||||
plant   280 TDVSSGGAISMSFSSLPFEEDEEKPSTNVN-IFTTMKVLVEKRWALKRLS-AVMAIAFGIGLVYY 342

  Fly   427 GIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITE--- 488
            |:.|.:|:...|:||::|...|:::||..:.::::.|:.::..........||:........
plant   343 GMPLALSNLDFNIYLSAAFNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSVLIFALHNMR 407

  Fly   489 --GHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSL 551
              .|..   |::...::..|:..:...:..:||.||:||.:||..:.....|..|..:.:|.:..
plant   408 IGNHGA---LQLALELISYFSACSAFNMEMIYTIELFPTCVRNSAIAMARQALVLGGVFSPIMVA 469

  Fly   552 LNKIEGHLLMTLLTAWS--IFG---GFVVLF---LPET 581
            ..:....        ||  :||   |.:.||   ||||
plant   470 AGRKNAF--------WSFGLFGLAIGLLGLFAVGLPET 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	127/527 (24%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	97/389 (25%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	111/448 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.970