DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and OCT3

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_173089.1	Gene:	OCT3 / 838209	AraportID:	AT1G16390	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	132/536 - (24%)
Similarity:	216/536 - (40%)	Gaps:	83/536 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SGLDPADDEDETDVIGDLMGHYGKWQLLMTVLLS---LFQVPNTFHISSSIYQAANKDFWCQRPA 132
            |.|.|....:||  |...:|.:|..|.|...|:|   .|....||   .:::..:...:.|
plant    17 SNLPPPRSLEET--IERCIGDFGWAQFLQAALVSFAWFFDAQQTF---ITVFTDSQPMWHC---- 72

  Fly   133 QLQHMPVATWRNLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNV 197
                             ||..|.:.:..:..||..|||:               :.|.::.|.:|
plant    73 -----------------DNSDRVDSVCNTSSSNLCTLPN---------------QTWSWDLNPHV 105

  Fly   198 GNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSD-KFGRKTMLFISAVLQTIFGLWLY 261
              :..|:|.|.|....||......|.||...||:....|:| ..|||.||.:|.::.::..:...
plant   106 --SIISEWGLQCAGSFLKGFPASSFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLSSMLTA 168

  Fly   262 ICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQ 326
            ..:|..:|..||.|.|....::....|:|:.|.|..|||...|....|...:.::.:..|.|:.:
plant   169 FSTSIWVYAFLRFLNGCGRATIGTCALVLSTELVGKKWRGQVGAMGFFCFTLGFLSLPMLGYINE 233

  Fly   327 --DYQRLQLCIGIPG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAA------KFNGRQLPA 382
              .::.|.:...||. |:.|.:...|.||||||:||||.:|...|:::.|      .|.......
plant   234 GNSWRNLYVWTSIPTLIYCCLVRSFVRESPRWLIVKGRKEEAVSILQSIASNAITMSFTNLCFEV 298

  Fly   383 DYQLTPPTQESSTQDV----TYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNS 443
            :..     |..|..||    ..|.|.|:..|..:....:.|.:.:||||:.|.:::...|:||..
plant   299 END-----QSKSNPDVYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLNFNLYLGV 358

  Fly   444 ALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTI 508
            ....|.|.||..:..:.|.|:.::.........:|::....|:.  ...|..|:|...::..|:.
plant   359 VFNALSEFPAFLITFFFIDKINRRDALIGFTALSGISSALIAVL--GQQLGSLQIVLELVSFFSA 421

  Fly   509 SAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWS--IFG 571
            .....:..:||.|::||.:||..:.....|.....:.:|.:....: |...       ||  :||
plant   422 CTAFNMTLIYTIEMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGR-ENQF-------WSYGLFG 478

  Fly   572 ------GFVVLFLPET 581
                  |..|..||||
plant   479 LIIGLCGLFVFGLPET 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	124/515 (24%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	95/378 (25%)
OCT3	NP_173089.1	MFS_OCT_plant	87..492	CDD:340936	109/436 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.970