Protein Alignment CG6006 and Slc22a8

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_112622.1
• Gene: Slc22a8 / 83500
• RGDID: 632286
• Length: 536
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 145/544 - (26%)
• Similarity: 239/544 - (43%)
• Gaps: 49/544 - (9%)

  Fly    87 DLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWRNLSGSVDN 151
            |.:|..|.:|.|...||:|..:....|....|:.|......|:.|......|.....:.:|..:.
  Rat     8 DRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPWVLPLDPNGKPEK 72

  Fly   152 CRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVAC-EKWEY-ETNDNVGNTWTSQWDLVCEKEHL 214
            |.|:..:.      ..:||:|.:...|      .| :.|.| .|.|.:    ..:|||||....|
  Rat    73 CLRFVHLP------NASLPNDTQRATE------PCLDGWIYNSTRDTI----VIEWDLVCSSNKL 121

  Fly   215 KNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLV 279
            |.:|:..|:.|:..||.:.|.|||:||||.:|..|.::....|.......|..:|:..|.|.|..
  Rat   122 KEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFRFLCGCS 186

  Fly   280 SVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCF 344
            ...::.|.:||.:|:|....|.|:.....:...|...|:|||||....::.|||....|......
  Rat   187 ISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQLTSSAPFFIFSL 251

  Fly   345 LWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTY--------- 400
            |.:.||||.|||::.|:..:..:.::..|.|||::...........:.:..:|:|.
  Rat   252 LSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFNLQKDITSAKVKYGLSD 316

  Fly   401 LFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVG 465
            |||.|.|||::.|....||:....||.:.:.:..||.|:|:...:.|.|:|||..:.:..::.:|
  Rat   317 LFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSLSYLG 381

  Fly   466 KKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNV 530
            ::......|:.||.|............|  |:....:.||..:|...:.:.:||:|||||.:|..
  Rat   382 RRITQSFLLLLAGGAILALIFVPSEMQL--LRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQT 444

  Fly   531 GVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETAVR----------- 584
            |:|..||.|.:..::.|.:.:..:::..:...:....::.||....||.||..|
  Rat   445 GMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGTTALLGGSAAFFLLETLNRPLPETIEDIQN 509

  Fly   585 -----QKTDNQGGSSANASAAKQV 603
                 |||..:    :.|..|.|:
  Rat   510 WHKQVQKTKQE----SEAEKASQI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	113/399 (28%)
Slc22a8	NP_112622.1	2A0119	11..503	CDD:273328	138/509 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	515..536		6/19 (32%)