DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and OCT4

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_188702.2	Gene:	OCT4 / 821613	AraportID:	AT3G20660	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	564	Identity:	149/564 - (26%)
Similarity:	245/564 - (43%)	Gaps:	99/564 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 IPPKQQAATPQSPAAAVSGLDPADDEDETDVIGDLM----GHYGKWQLLMTVLLSLFQVPNTFHI 114
            ||.|::|                 :.:|...|.:::    |.:|:|||...||..:......||.
plant    20 IPVKKEA-----------------EGEERLCIDEMLQRYCGEFGRWQLKHFVLTCIAWALEAFHT 67

  Fly   115 SSSIYQAANKDFWCQRPAQLQHMPVATWRNLS-----GSVDNCRRWEGIDWSQVSNETTLPSDWK 174
            ...|       |..|.|         .||.:.     ||: ||.    :|          ||.|:
plant    68 MVMI-------FADQEP---------EWRCVGSDCRVGSL-NCE----LD----------PSSWE 101

  Fly   175 TPAEMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSD- 238
            ..|                  ..|::..|:|.|:|..::...:.:..|..|...|..:.|:|||
plant   102 WTA------------------GKGSSTVSEWGLICGDKYKVGLVQALFFAGCMIGAGVFGHLSDS 148

  Fly   239 KFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIA 303
            |.|||..|.:..::..|||:......::..|:.||.|.|..:..|..:..:||.|.:....|.:|
plant   149 KLGRKGSLTVVCIINAIFGIATAFSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRGVA 213

  Fly   304 GMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVP---ESPRWLLVKGRIDEV 365
            ||...:.......::||:||:.:.::.|.:...:|.  |.||..|:|   |||||.||:|::||.
plant   214 GMSTFYFFSAGIAVLSGIAYVFRSWRELFIVSSLPS--LLFLLIVIPFISESPRWYLVRGKVDEA 276

  Fly   366 RRIIEAAAKFNGRQLPADYQLT------------PPTQESSTQDVTYLFRSSYLRRISICFFCIW 418
            .:::.:.||.|||.:||...|.            ....|.|.:||   ..|..:|...:....|.
plant   277 MKLMHSIAKTNGRHIPAGVTLALDDDVENNNGERNTAVEGSLKDV---ILSPLMRMRLVISVAIS 338

  Fly   419 FTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCC 483
            ||:::||||:.||:.:...|:|||..:..:.|:||.|:...::.|.|:|.|...|...:.|.|..
plant   339 FTVSIVYYGLSLNVGNLKTNLYLNVFVNAVSEMPAFAITAVLLDKYGRKPLSIGTQWFSCVFCLV 403

  Fly   484 AAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPY 548
            .....|......:::...::|.|.::....::.:|.|||:||.:||..:|....||.:..||.|:
plant   404 GFSVWGAGPWKSVRMVSGVLGIFGMAGTYNLLFIYIAELFPTVVRNAALGCATQAAQMGAILAPF 468

  Fly   549 LSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETAVRQKTDNQGG 592
            :.:|.:   .|...:.....:.||.:..:||||..:...|...|
plant   469 VVVLGE---ELPFGVFAVCGLVGGGLAFYLPETLNKPLYDTMFG 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	139/511 (27%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	108/372 (29%)
OCT4	NP_188702.2	MFS_OCT_plant	90..496	CDD:340936	121/446 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.970