Protein Alignment CG6006 and slc22a3

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001107932.1
• Gene: slc22a3 / 797890
• ZFINID: ZDB-GENE-080204-92
• Length: 554
• Species: Danio rerio
• Alignment Length: 541
• Identity: 141/541 - (26%)
• Similarity: 244/541 - (45%)
• Gaps: 85/541 - (15%)

  Fly    90 GHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQH---MPVATWRNLS----- 146
            |.:|.:|..::||.||..:...|.:...::.....|.|| :.|.||.   ......|:|:
Zfish    12 GDFGFYQKRISVLGSLPILLLAFVLIGVVFLGYTPDHWC-KTASLQEKCGFSEEQVRDLTVPRTG 75

  Fly   147 --GSVDNCRRWE---------GIDWSQVSNETTLPSDWKTPAEMDKKLVAC-EKWEYETNDNVGN 199
              |:...|.:::         ..:.|..:|.|              .|.|| |.|.:..|   ..
Zfish    76 ARGAFSKCVKFDDALRNGSALSCNISIFNNST--------------HLSACNEGWTFNEN---RT 123

  Fly   200 TWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLY-IC 263
            |..:::.||||...|.::.::....|...|.:::|||:|:||||     |..:.:||||.:. .|
Zfish   124 TIVTEFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGRK-----SCFIASIFGLGVSGTC 183

  Fly   264 SSFELY----LTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYL 324
            ..|..|    |..|.|.|..:.....:..:|.||:.....|....:.:.....:..:::..|||.
Zfish   184 IIFSPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKFVSVMSRTFYSLGLVLLPALAYY 248

  Fly   325 TQDYQRLQLCIGIPG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQ--- 385
            ...::.|||.:.:|. |||.:.| |:||||||||.:.:..|...|:::.||.|.|.||.|:.
Zfish   249 IPSWRNLQLAMTLPTFIFLIYHW-VIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFHEMD 312

  Fly   386 -LTPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLV 449
             |....:|........||::..:|:.:......|||..:|:.|::|.:...|.||:|:..::.:|
Zfish   313 LLIEKQEEIMRPSYKDLFKTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLISAVV 377

  Fly   450 EIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTI 514
            |:|...:..:::.::|::.|........|.|  |.|:.....::.||:.|..::|:..::.||..
Zfish   378 ELPTGLIFYFLVDRIGRRPLMATVNFIGGAA--CLAVPFISPNISWLRRTIAIVGRLAVAIGNET 440

  Fly   515 MPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWS----------- 568
            :.....||||||:||:||..|:.|:.:..::.|:          :|..|.:.|.
Zfish   441 VNFANTELYPTPLRNLGVSVCSSASDIGAVVAPF----------ILYRLASIWQELPLLVYGVMS 495

  Fly   569 -IFGGFVVLF-------LPET 581
             ::.|.|:|.       ||||
Zfish   496 VLYSGLVMLLPEMKGVDLPET 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	112/418 (27%)
slc22a3	NP_001107932.1	MFS_SLC22A1_2_3	105..506	CDD:340937	118/435 (27%)