DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and Slc22a16

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_038955098.1	Gene:	Slc22a16 / 682934	RGDID:	1592810	Length:	852	Species:	Rattus norvegicus

Alignment Length:	570	Identity:	132/570 - (23%)
Similarity:	244/570 - (42%)	Gaps:	93/570 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 DVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWRNLSG 147
            ::|.|.:||:|::|:.:.::.:...:....|..||::.:...:..|:.|..::.   |.:||:|.
  Rat     7 ELIFDHVGHFGRFQIALYLICAYQSISCGIHFLSSVFMSIIPEHACKPPGTVRK---AVFRNVSA 68

  Fly   148 SVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVAC---EKWEY--------ETNDNVGNTW 201
                   |...|...:          ::|...|..:|..   |.||.        |...::|..:
  Rat    69 -------WRLEDILAL----------RSPEHKDHIMVELHDGEIWELTRCSRTWRENTSHLGYEY 116

  Fly   202 T----------------SQW--------DLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGR 242
            :                |:|        :|||:::...|:.:..|:..:..|.|...||||:|||
  Rat   117 SGYKRDSPCSDGYIYDQSKWRSSVVGSFNLVCDQKWYANMIQPLFIFAMLLGAITFSYLSDRFGR 181

  Fly   243 KTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMY- 306
            :..|:.:.:....||:.......:..::..|..|.:.|........:..:|::..:.||.|.|:
  Rat   182 RVALWCTTIGVFFFGIGSIFIFDYFSFMAARFFLVMTSSGYFVVVFVYVMEFIGRESRTWASMHL 246

  Fly   307 NLFPLPISYMIISGLAYLTQD---YQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRI 368
            |.| ..|..|:::.::||.:.   ||.:...:..|.|..|::   :||:|.|||.:||..|.:.:
  Rat   247 NTF-FAIGTMLVALVSYLVKTWWLYQIILWTVTAPFILCCWM---LPETPFWLLSEGRYKEAQGV 307

  Fly   369 IEAAAKFNGRQLPADYQLTPPTQESSTQDVTY----------------LFRSSYLRRISICFFCI 417
            ::|.|.:| :....|      ..|..:.|||.                |||:..:.::::..:..
  Rat   308 VDAMAVWN-KSSSCD------LIELLSLDVTRSHDKSHKGAGKPSLGDLFRNPDIAKMTLIVWLD 365

  Fly   418 WFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACC 482
            |||:||.||...:.......:.:|...|.|.|||||.......:.:||::......|:.:...|.
  Rat   366 WFTVNLGYYVFAMEAVRRKEHEHLYYLLVGAVEIPAYVFLCIWMQRVGRRKTMLTFLLMSSFICV 430

  Fly   483 CAAITEGHADLL-WLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILT 546
            ...:....:|.. ..|....:..|..:.:....:.:||||||||.:|.:.||:.|:.:.:|.::.
  Rat   431 VYVVIPSDSDTAKEAKGAVALFVKVAVGSVFAFIYLYTAELYPTIMRCLAVGSSNMVSHVASMVI 495

  Fly   547 PYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETAVR------QKTDNQ 590
            |.....:|:...|...|....:|..|.:.|.||||..|      :.|:.|
  Rat   496 PLSQHFSKVWIFLPQILFGTLAILSGLLSLNLPETQNRPMISTWETTEEQ 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	125/546 (23%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	94/377 (25%)
Slc22a16	XP_038955098.1	MFS	118..528	CDD:421695	100/420 (24%)
Slc22a16	XP_038955098.1	PHA03169	645..>852	CDD:223003
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010