Protein Alignment CG6006 and SLC22A2

DIOPT Version :9

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 149/531 - (28%)
• Similarity: 254/531 - (47%)
• Gaps: 52/531 - (9%)

  Fly    85 IGDLMGHYGK---WQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATW---R 143
            :.|::.|.|:   :|..|..||:|............::.....|..|:.|...:......|   .
Human     5 VDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELSLRCGWSPAE 69

  Fly   144 NLSGSVD-----------NCRRWEGIDWSQV------------SNETTLPSDWKTPAEMDKKLVA 185
            .|:.:|.           .|||:| :||:|.            :|.:.||            |..
Human    70 ELNYTVPGPGPAGEASPRQCRRYE-VDWNQSTFDCVDPLASLDTNRSRLP------------LGP 121

  Fly   186 C-EKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFIS 249
            | :.|.|||   .|::..::::|||....:.::.:....:|...|.:..||::|:||||..|..:
Human   122 CRDGWVYET---PGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTT 183

  Fly   250 AVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPIS 314
            .::....|:.:.|..::...|..|.:.||||.:....|.||..|:|..::|...|::......:.
Human   184 VLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVG 248

  Fly   315 YMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQ 379
            .::::|:||....::.||..:.:|..|....::.:|||||||:.:.:..|..|||:..||.||:.
Human   249 LLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKS 313

  Fly   380 LPADYQ---LTPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYL 441
            |||..|   |...|.:........|.|:..:|:.::.....|||.:::|.|:|::|...|.|:||
Human   314 LPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYL 378

  Fly   442 NSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKF 506
            :...:.|||.||..:.:..|.::|:::.:.|:.:.||.||..:....|  ||.||||....:|:.
Human   379 DFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVFIPG--DLQWLKIIISCLGRM 441

  Fly   507 TISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSL-LNKIEGHLLMTLLTAWSIF 570
            .|:....|:.:..||||||.|||:||..|:....:..|:||:|.. |..|...|.:.:.....:.
Human   442 GITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLV 506

  Fly   571 GGFVVLFLPET 581
            .|.:||.||||
Human   507 AGGLVLLLPET 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	146/524 (28%)
		MFS	222..579	CDD:119392	111/360 (31%)
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	147/523 (28%)
		MFS	124..492	CDD:119392	114/372 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020