DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	549	Identity:	150/549 - (27%)
Similarity:	268/549 - (48%)	Gaps:	54/549 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 DETDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWR- 143
            |.|.::.. :|.:|.:|..:.|.:.|..:...||:...::.|.:...:|.....|:..|..|..
Zfish     3 DFTQILSS-VGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEK 66

  Fly   144 --NLS------GSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMD---------KKLVAC-EKWE 190
              ||:      |..::|:.:                   ||.|||         ....:| :.|.
Zfish    67 QLNLTVPLDSKGQYESCKMF-------------------TPVEMDIEDIEHYGINTTTSCIDGWV 112

  Fly   191 YETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTI 255
            |:...: .:|..:::|||||.:.....::..::.|:..|.::.|.::||:||:....:|..||.:
Zfish   113 YKAPKD-SSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFL 176

  Fly   256 FGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISG 320
            .|:.:....:..:|:.||.::|.....::.:..:|..|:.....|.:..:.:.....|..|::||
Zfish   177 SGVGVAFSPNIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIGLMLLSG 241

  Fly   321 LAYLTQDYQRLQLCIGIP-GIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLP--- 381
            :||..::::.|||.:..| |:|..:.| ::|||.||||.:|::|..:|.|..||:.|||::.
Zfish   242 VAYGIRNWRVLQLVLSAPVGLFFIYYW-ILPESARWLLTQGKLDSAKREILKAARINGRKVSENL 305

  Fly   382 ADYQLTPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALA 446
            .|......|.:|||  :..|||..|||:.::....:||..:|||||:.||:.:||.::||...:.
Zfish   306 LDKMEAENTAKSST--MIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIF 368

  Fly   447 GLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFL-MMGKFTISA 510
            |:.|.||......:|.:.|::......|:..|.||...........::   :|.: ::|||:::|
Zfish   369 GMAEFPARLSCFPLIQRFGRRICQSVVLLLGGTACLIIPAIPAKYPIV---VTVIAVIGKFSLAA 430

  Fly   511 GNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVV 575
            ..:|:.|||||||||.:|..|||..::.|.:|.||.|.:.||:.....:.|.:..:....||.:.
Zfish   431 SFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALT 495

  Fly   576 LFLPETA---VRQKTDNQGGSSANASAAK 601
            ..||||.   ::..||.....|...:..|
Zfish   496 FLLPETLNTDLQDHTDIPADESMTVTEVK 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	142/514 (28%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	110/361 (30%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020