Protein Alignment CG6006 and SVOP

DIOPT Version :9

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_061181.1
• Gene: SVOP / 55530
• HGNCID: 25417
• Length: 548
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 124/548 - (22%)
• Similarity: 227/548 - (41%)
• Gaps: 135/548 - (24%)

  Fly   133 QLQHMPVATWRNLSGSV---DNCRRWE----------GIDWSQVSNETTLPSDWKTPAEMDKKLV 184
            ||:.:||..:|....|.   |:....|          |::..::.:...:|.::..|.: |..:|
Human     7 QLRQLPVVKFRRTGESARSEDDTASGEHEVQIEGVHVGLEAVELDDGAAVPKEFANPTD-DTFMV 70

  Fly   185 --ACE-----KWEYETNDNVGNTWTS-----------------QWDLVCEKEHLKNVAEMFFLLG 225
              |.|     |::::.:...|..|.:                 :|.|...:..|  :..:.| :|
Human    71 EDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVAL--LTSVVF-VG 132

  Fly   226 VATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGL----VSVSVTY- 285
            :.:...:.|.:||::||||.|.||.:....:|:.......:...|.||.|:|.    |..|||.
Human   133 MMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY 197

  Fly   286 ---------SGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIF 341
                     :..||.||..   |    .:..:|.:.::..::..|.     ::.|.:...:|.:.
Human   198 AEFLPMKARAKCILLIEVF---W----AIGTVFEVVLAVFVMPSLG-----WRWLLILSAVPLLL 250

  Fly   342 LCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSY 406
            ...|.|.:|||.|:.::.|..::....::..|..||..:|.. :|....||...: :..|| :.:
Human   251 FAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLG-KLIISRQEDRGK-MRDLF-TPH 312

  Fly   407 LRRISICFFCIWFTMNLVYYGIILNMSSF--GGNV-------------------------YLNSA 444
            .|..::..:.|||:....|||::|..:..  .|:|                         |::..
Human   313 FRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGISSRKKAVEAKCSLACEYLSEEDYMDLL 377

  Fly   445 LAGLVEIPAIAVAMYIITKVGKK---------WLFCATL--ICAGVACCCAAITEGHADLLWLKI 498
            ...|.|.|.:.|.::||.::|:|         :.||:.|  ||.|            .::|.|
Human   378 WTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVG------------RNVLTL-- 428

  Fly   499 TFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTL 563
             .|.:.:..||.|.....|||.|:|||..|.:|:|.|:..|.:..::||:::.: .:|..:.:||
Human   429 -LLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQV-MLESSVYLTL 491

  Fly   564 LTAWSIFGGFVVL------FLP-ETAVR 584
                :::.|..:|      ||| ||..|
Human   492 ----AVYSGCCLLAALASCFLPIETKGR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	121/543 (22%)
		MFS	222..579	CDD:119392	98/414 (24%)
SVOP	NP_061181.1	MFS_SVOP	87..509	CDD:340999	103/459 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910