DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and oatx

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	566	Identity:	149/566 - (26%)
Similarity:	272/566 - (48%)	Gaps:	77/566 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 DLMGHYGKWQLLMTVLLSLFQVPNTFHISSSI---YQAANKDFWCQRPAQLQHMPVATWRNL--- 145
            |.:|.:|::|::...|||   :|.....|.::   :.|...:..|:.|.....|..:|...|
Zfish     8 DEVGGFGRFQMIHVTLLS---IPGLLMASQNLLNNFTAGVPEHHCRIPNVTTAMNDSTTTLLRAF 69

  Fly   146 -----SGSVDNCRRWEGIDWSQVS------NETTLPSDWKTPAEMDKKLVAC-EKWEYETNDNVG 198
                 |.::..|.|::...|..::      |.|.|.::            .| :.|.|:.::.:.
Zfish    70 IPLDSSLTLSKCSRYKDTQWHLITDKLSHGNATELQTE------------GCADGWTYDKSEFIS 122

  Fly   199 NTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYIC 263
            :. .|:|||||....||.:::..::.||.||.||.|.|||:||||.:|..|.....:.|.:..:.
Zfish   123 SI-VSEWDLVCTLRPLKQMSQTIYMGGVLTGAIIFGGLSDRFGRKALLIWSYFQLALLGSFTALA 186

  Fly   264 SSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDY 328
            .|:.:|...|.|.|:....|..:.:.|.:|::..|.||:.|..:.|......|:::|:||..:|:
Zfish   187 PSYVVYCIFRFLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDW 251

  Fly   329 QRLQLCIGIPGIFLCFL---WFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPT 390
            :::|:.:.:| .|:.|:   ||  .||.|||::.||.:|..:::...||.||:....: ::|...
Zfish   252 RKIQMAVCLP-FFIFFMYSWWF--SESARWLVLNGRSEEALKLLHRVAKINGKPEMTE-KITLEE 312

  Fly   391 QESSTQ----------DVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSAL 445
            .||..|          .|..|.|:..:|:||:|...:||:.:..|||:.:::..||.|:||...:
Zfish   313 LESHMQKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLMQVI 377

  Fly   446 AGLVEIPAIAVAMYIITKVGKK------WLFCATLICAGVACCCAAITEGHADLLWLKITFLMMG 504
            .|.|:.||..||:.:::.:|::      .|..|::|.|.:     .:.|   |:...:....::|
Zfish   378 FGAVDFPAKLVALLMLSFLGRRLTQGACLLVSASIIFANI-----FVPE---DMQVTRTALAVLG 434

  Fly   505 KFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSI 569
            |...||..|.:.::|.|||||.||..|:|..:..:.:..:..|.:.:|:.|...|...:....::
Zfish   435 KGFTSASFTCVYLFTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIVYGGSAV 499

  Fly   570 FGGFVVLFLPETA----------VRQKTDNQGGSSANASA--AKQV 603
            ..|.:...||||.          |.:|.:.:..::.:.:.  .|||
Zfish   500 IAGLIAFLLPETLNIPLPDTIDDVEEKWEKKNNTAEDLALQDVKQV 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	141/527 (27%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	107/375 (29%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020